Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
Caur_2274TIGRFAM: CRISPR-associated RAMP protein, Csx10 family; KEGG: csc:Csac_0486 protein of unknown function DUF324. (542 aa)    
Predicted Functional Partners:
Caur_2275
PFAM: protein of unknown function DUF324; KEGG: swo:Swol_2526 uncharacterized protein predicted to be involved in DNA repair (RAMP superfamily)-like protein.
 
    0.951
Caur_2272
KEGG: swo:Swol_2528 hypothetical protein.
 
     0.950
Caur_2273
KEGG: cth:Cthe_3210 protein of unknown function DUF324.
 
    0.949
Caur_2277
PFAM: RNA binding S1 domain protein; KEGG: csc:Csac_0489 protein of unknown function DUF324.
 
     0.946
Caur_2271
KEGG: csc:Csac_0484 hypothetical protein.
       0.793
Caur_2276
Hypothetical protein.
       0.792
Caur_2291
KEGG: rrs:RoseRS_1438 hypothetical protein.
 
     0.746
Caur_2296
PFAM: protein of unknown function DUF324; KEGG: rrs:RoseRS_1443 protein of unknown function DUF324.
 
    0.603
cas2-1
CRISPR-associated protein Cas2; CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.
 
     0.599
Caur_2270
PFAM: regulatory protein LuxR; Sigma-70 region 4 type 2; KEGG: rca:Rcas_3296 transcriptional regulator, LuxR family.
       0.561
Your Current Organism:
Chloroflexus aurantiacus
NCBI taxonomy Id: 324602
Other names: C. aurantiacus J-10-fl, Chloroflexus aurantiacus ATCC 29366, Chloroflexus aurantiacus DSM 635, Chloroflexus aurantiacus J-10-fl, Chloroflexus aurantiacus str. J-10-fl, Chloroflexus aurantiacus strain J-10-fl
Server load: low (34%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.