Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
Caur_2280PFAM: beta-lactamase domain protein; Excalibur domain protein; KEGG: rrs:RoseRS_4309 beta-lactamase domain protein. (439 aa)    
Predicted Functional Partners:
Caur_2622
PFAM: ComEC/Rec2-related protein; KEGG: rrs:RoseRS_1609 ComEC/Rec2-related protein.
   
 0.946
Caur_2279
KEGG: rrs:RoseRS_4310 hypothetical protein.
       0.743
glyA
Glycine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
      0.645
Caur_2278
SMART: helix-turn-helix domain protein; KEGG: cbe:Cbei_3660 helix-turn-helix domain protein.
   
  
 0.596
Caur_2281
TIGRFAM: zinc-binding alcohol dehydrogenase family protein; PFAM: Alcohol dehydrogenase zinc-binding domain protein; Alcohol dehydrogenase GroES domain protein; KEGG: ana:all0879 alcohol dehydrogenase.
     
 0.595
Caur_2959
Hypothetical protein; KEGG: mma:MM_3056 competence-like protein.
     0.538
Caur_1943
PFAM: peptidase A24A prepilin type IV; peptidase A24A domain protein; KEGG: rca:Rcas_3416 peptidase A24A domain protein.
  
  
 0.512
Caur_1845
KEGG: rrs:RoseRS_1875 amidophosphoribosyltransferase-like protein.
  
  
 0.459
Caur_0756
TIGRFAM: cell division protein FtsW; PFAM: cell cycle protein; KEGG: rca:Rcas_1096 cell division protein FtsW; Belongs to the SEDS family.
 
     0.447
rsmA
Dimethyladenosine transferase; Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits.
 
     0.422
Your Current Organism:
Chloroflexus aurantiacus
NCBI taxonomy Id: 324602
Other names: C. aurantiacus J-10-fl, Chloroflexus aurantiacus ATCC 29366, Chloroflexus aurantiacus DSM 635, Chloroflexus aurantiacus J-10-fl, Chloroflexus aurantiacus str. J-10-fl, Chloroflexus aurantiacus strain J-10-fl
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