STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Caur_2509KEGG: rca:Rcas_3871 methylmalonyl-CoA mutase, large subunit; TIGRFAM: methylmalonyl-CoA mutase, large subunit; PFAM: methylmalonyl-CoA mutase. (717 aa)    
Predicted Functional Partners:
Caur_2508
KEGG: rrs:RoseRS_0545 methylmalonyl-CoA mutase, large subunit; TIGRFAM: methylmalonyl-CoA mutase, large subunit; PFAM: methylmalonyl-CoA mutase; cobalamin B12-binding domain protein.
 
 
0.999
Caur_2507
TIGRFAM: LAO/AO transport system ATPase; PFAM: ArgK protein; KEGG: rrs:RoseRS_0546 LAO/AO transport system ATPase.
  
 0.992
Caur_3037
PFAM: Glyoxalase/bleomycin resistance protein/dioxygenase; KEGG: rrs:RoseRS_0480 glyoxalase/bleomycin resistance protein/dioxygenase.
 
  
 0.990
Caur_0043
TIGRFAM: LAO/AO transport system ATPase; PFAM: ArgK protein; SMART: AAA ATPase; KEGG: rrs:RoseRS_2025 LAO/AO transport system ATPase.
  
 0.978
Caur_0042
PFAM: cobalamin B12-binding domain protein; KEGG: rca:Rcas_2998 cobalamin B12-binding domain protein.
 
 0.967
smtB
L-carnitine dehydratase/bile acid-inducible protein F; Involved in the 3-hydroxypropionate cycle used for autotrophic carbon dioxide fixation. Catalyzes the transfer of CoA moiety from succinyl-CoA to L-malate to yield L-malyl-CoA (By similarity).
    
 0.951
smtA
L-carnitine dehydratase/bile acid-inducible protein F; Involved in the 3-hydroxypropionate cycle used for autotrophic carbon dioxide fixation. Catalyzes the transfer of CoA moiety from succinyl-CoA to L-malate to yield L-malyl-CoA (By similarity).
    
 0.951
sucD
succinyl-CoA synthetase, alpha subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.
    
 0.947
Caur_0249
PFAM: pyruvate flavodoxin/ferredoxin oxidoreductase domain protein; KEGG: rca:Rcas_2308 pyruvate flavodoxin/ferredoxin oxidoreductase domain protein.
    
 0.941
Caur_0952
PFAM: pyruvate ferredoxin/flavodoxin oxidoreductase; pyruvate flavodoxin/ferredoxin oxidoreductase domain protein; KEGG: mgm:Mmc1_1749 pyruvate flavodoxin/ferredoxin oxidoreductase domain protein.
    
 0.941
Your Current Organism:
Chloroflexus aurantiacus
NCBI taxonomy Id: 324602
Other names: C. aurantiacus J-10-fl, Chloroflexus aurantiacus ATCC 29366, Chloroflexus aurantiacus DSM 635, Chloroflexus aurantiacus J-10-fl, Chloroflexus aurantiacus str. J-10-fl, Chloroflexus aurantiacus strain J-10-fl
Server load: low (22%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.