STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
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Cooccurrence
Coexpression
Experiments
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[Homology]
Score
Caur_2802PFAM: NAD-dependent epimerase/dehydratase; short-chain dehydrogenase/reductase SDR; 3-beta hydroxysteroid dehydrogenase/isomerase; KR domain protein; KEGG: rrs:RoseRS_2303 short-chain dehydrogenase/reductase SDR; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (252 aa)    
Predicted Functional Partners:
Caur_2803
Transaldolase; Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway; Belongs to the transaldolase family. Type 3B subfamily.
  
  
 0.774
Caur_2804
PFAM: phosphoribulokinase/uridine kinase; KEGG: gvi:glr4424 phosphoribulokinase.
   
   0.763
Caur_2801
KEGG: rca:Rcas_2317 N-acetylmuramyl-L-alanine amidase, negative regulator of AmpC, AmpD.
     
 0.745
hisD
Histidinol dehydrogenase; Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine.
 
  
   0.649
Caur_0613
PFAM: AMP-dependent synthetase and ligase; Enoyl-CoA hydratase/isomerase; Alcohol dehydrogenase GroES domain protein; KEGG: rrs:RoseRS_3202 AMP-dependent synthetase and ligase.
  
 0.624
Caur_2034
Propionyl-CoA carboxylase; PFAM: carboxyl transferase; KEGG: rca:Rcas_0975 propionyl-CoA carboxylase.
 
 
 0.613
Caur_3221
PFAM: Enoyl-CoA hydratase/isomerase; 3-hydroxyacyl-CoA dehydrogenase domain protein; 3-hydroxyacyl-CoA dehydrogenase NAD-binding; KEGG: rca:Rcas_1887 3-hydroxyacyl-CoA dehydrogenase NAD-binding.
  
 0.543
Caur_3631
PFAM: MaoC domain protein dehydratase; KEGG: mmw:Mmwyl1_2239 MaoC domain protein dehydratase.
  
 0.454
guaB
Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family.
   
 
 0.452
mch
MaoC domain protein dehydratase; Involved in the glyoxylate assimilation cycle used to regenerate acetyl-CoA and produce pyruvate as universal precursor for biosynthesis. Catalyzes the reversible dehydration of beta-methylmalyl- CoA ((2R,3S)-beta-methylmalyl-CoA) to yield mesaconyl-CoA (methylfumaryl-CoA).
 
 0.447
Your Current Organism:
Chloroflexus aurantiacus
NCBI taxonomy Id: 324602
Other names: C. aurantiacus J-10-fl, Chloroflexus aurantiacus ATCC 29366, Chloroflexus aurantiacus DSM 635, Chloroflexus aurantiacus J-10-fl, Chloroflexus aurantiacus str. J-10-fl, Chloroflexus aurantiacus strain J-10-fl
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