Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
Caur_3036Histidine kinase; PFAM: GAF domain protein; ATP-binding region ATPase domain protein; histidine kinase A domain protein; KEGG: rca:Rcas_1057 multi-sensor signal transduction histidine kinase. (726 aa)    
Predicted Functional Partners:
Caur_2069
PFAM: response regulator receiver; KEGG: reh:H16_B2354 signal transduction histidine kinase containing two receiver domains (hybrid).
 
 
 0.958
Caur_1469
PFAM: response regulator receiver; KEGG: azo:azo3457 putative pilus biogenese protein.
 
 
 
 0.846
Caur_1862
Response regulator receiver; PFAM: adenylyl cyclase class-3/4/guanylyl cyclase; response regulator receiver; GAF domain protein; PAS fold-4 domain protein; PAS fold domain protein; KEGG: rrs:RoseRS_2694 putative PAS/PAC sensor protein.
 
 
 0.824
Caur_1668
PFAM: response regulator receiver; KEGG: rrs:RoseRS_0035 response regulator receiver protein.
 
 
 0.822
Caur_2815
PFAM: response regulator receiver; KEGG: mbu:Mbur_0695 response regulator receiver.
 
 
 0.819
Caur_1771
PFAM: response regulator receiver; KEGG: rrs:RoseRS_3877 response regulator receiver protein.
 
 
 0.818
Caur_0959
PFAM: response regulator receiver; transcriptional regulator domain protein; KEGG: rca:Rcas_2795 two component transcriptional regulator, winged helix family.
 
 
 0.809
Caur_0031
TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain containing protein; response regulator receiver; KEGG: rca:Rcas_3221 response regulator receiver modulated diguanylate cyclase.
   
 0.801
Caur_1676
PFAM: response regulator receiver; KEGG: rrs:RoseRS_0337 response regulator receiver protein.
 
 
 
 0.800
Caur_0854
PFAM: response regulator receiver; KEGG: rrs:RoseRS_0997 response regulator receiver protein.
 
 
 0.796
Your Current Organism:
Chloroflexus aurantiacus
NCBI taxonomy Id: 324602
Other names: C. aurantiacus J-10-fl, Chloroflexus aurantiacus ATCC 29366, Chloroflexus aurantiacus DSM 635, Chloroflexus aurantiacus J-10-fl, Chloroflexus aurantiacus str. J-10-fl, Chloroflexus aurantiacus strain J-10-fl
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