Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
Caur_3121PFAM: dehydrogenase E1 component; KEGG: sus:Acid_0352 pyruvate dehydrogenase (acetyl-transferring). (321 aa)    
Predicted Functional Partners:
Caur_3122
PFAM: Transketolase central region; Transketolase domain protein; KEGG: sus:Acid_0353 transketolase, central region.
 0.998
Caur_1334
PFAM: Transketolase central region; Transketolase domain protein; KEGG: bpu:BPUM_1172 pyruvate dehydrogenase (acetyl-transferring) E1 component beta subunit.
 0.995
Caur_1692
PFAM: Transketolase central region; Transketolase domain protein; KEGG: rrs:RoseRS_2416 transketolase, central region.
 0.995
Caur_1973
Transketolase central region; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2.
 0.995
Caur_3671
PFAM: Transketolase central region; Transketolase domain protein; KEGG: btl:BALH_2493 acetoin dehydrogenase (TPP-dependent) E1 component beta subunit.
 0.995
Caur_1333
PFAM: biotin/lipoyl attachment domain-containing protein; catalytic domain of components of various dehydrogenase complexes; E3 binding domain protein; KEGG: tte:TTE0188 Dihydrolipoamide acyltransferases.
 
 0.862
Caur_1974
Dihydrolipoyllysine-residue succinyltransferase; PFAM: biotin/lipoyl attachment domain-containing protein; catalytic domain of components of various dehydrogenase complexes; E3 binding domain protein; KEGG: rca:Rcas_2011 dihydrolipoyllysine-residue succinyltransferase.
 0.843
Caur_2840
TIGRFAM: dihydrolipoamide dehydrogenase; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; glucose-inhibited division protein A; pyridine nucleotide-disulphide oxidoreductase dimerisation region; KEGG: rrs:RoseRS_3003 dihydrolipoamide dehydrogenase.
 
 0.841
Caur_1691
PFAM: biotin/lipoyl attachment domain-containing protein; catalytic domain of components of various dehydrogenase complexes; E3 binding domain protein; KEGG: rrs:RoseRS_1675 catalytic domain of components of various dehydrogenase complexes.
 
 0.813
Caur_3670
PFAM: alpha/beta hydrolase fold; biotin/lipoyl attachment domain-containing protein; peptidase S15; E3 binding domain protein; KEGG: rle:pRL80022 hypothetical protein.
 
 0.812
Your Current Organism:
Chloroflexus aurantiacus
NCBI taxonomy Id: 324602
Other names: C. aurantiacus J-10-fl, Chloroflexus aurantiacus ATCC 29366, Chloroflexus aurantiacus DSM 635, Chloroflexus aurantiacus J-10-fl, Chloroflexus aurantiacus str. J-10-fl, Chloroflexus aurantiacus strain J-10-fl
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