STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Caur_3206TIGRFAM: DNA protecting protein DprA; PFAM: SMF family protein; KEGG: rrs:RoseRS_4590 DNA protecting protein DprA. (361 aa)    
Predicted Functional Partners:
topA
DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...]
   
 0.913
Caur_1366
KEGG: rrs:RoseRS_3748 Mg chelatase, subunit ChlI; TIGRFAM: Mg chelatase, subunit ChlI; PFAM: magnesium chelatase ChlI subunit; SMART: AAA ATPase.
 
 0.908
Caur_1845
KEGG: rrs:RoseRS_1875 amidophosphoribosyltransferase-like protein.
 
 
 0.900
Caur_2622
PFAM: ComEC/Rec2-related protein; KEGG: rrs:RoseRS_1609 ComEC/Rec2-related protein.
 
  
 0.873
Caur_1943
PFAM: peptidase A24A prepilin type IV; peptidase A24A domain protein; KEGG: rca:Rcas_3416 peptidase A24A domain protein.
  
  
 0.871
Caur_2698
PFAM: protein of unknown function UPF0102; KEGG: rrs:RoseRS_1723 protein of unknown function UPF0102; Belongs to the UPF0102 family.
 
  
 0.689
Caur_3534
Diguanylate cyclase; KEGG: ava:Ava_2710 putative diguanylate cyclase/phosphodiesterase (GGDEF & EAL domains) with PAS/PAC sensor(s); TIGRFAM: PAS sensor protein; diguanylate cyclase; PFAM: GGDEF domain containing protein; EAL domain protein; response regulator receiver; PAS fold-3 domain protein; PAS fold-4 domain protein; PAS fold domain protein; SMART: PAS domain containing protein; PAC repeat-containing protein.
   
    0.663
Caur_1013
PFAM: cyclic nucleotide-binding; Stage II sporulation E family protein; SMART: protein phosphatase 2C domain protein; KEGG: sfu:Sfum_4027 cyclic nucleotide-binding protein.
  
  
 0.654
Caur_2536
PFAM: Alkaline phosphatase; KEGG: rrs:RoseRS_1990 alkaline phosphatase.
  
    0.652
pyrB
TIGRFAM: aspartate carbamoyltransferase; PFAM: aspartate/ornithine carbamoyltransferase Asp/Orn-binding region; aspartate/ornithine carbamoyltransferase carbamoyl-P binding domain; KEGG: rca:Rcas_2434 aspartate carbamoyltransferase; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.
      0.650
Your Current Organism:
Chloroflexus aurantiacus
NCBI taxonomy Id: 324602
Other names: C. aurantiacus J-10-fl, Chloroflexus aurantiacus ATCC 29366, Chloroflexus aurantiacus DSM 635, Chloroflexus aurantiacus J-10-fl, Chloroflexus aurantiacus str. J-10-fl, Chloroflexus aurantiacus strain J-10-fl
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