STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Caur_3207PFAM: NUDIX hydrolase; KEGG: rca:Rcas_0219 NUDIX hydrolase; Belongs to the Nudix hydrolase family. (157 aa)    
Predicted Functional Partners:
Caur_0446
PFAM: NUDIX hydrolase; KEGG: rrs:RoseRS_3464 NUDIX hydrolase; Belongs to the Nudix hydrolase family.
 
     0.588
Caur_2026
TIGRFAM: HAD-superfamily hydrolase, subfamily IIA; HAD-superfamily hydrolase, subfamily IA, variant 3; PFAM: Haloacid dehalogenase domain protein hydrolase; KEGG: rrs:RoseRS_1310 HAD-superfamily hydrolase, subfamily IIA; Belongs to the HAD-like hydrolase superfamily.
      0.505
nadE
NAD+ synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source.
  
  
 0.501
Caur_1407
TIGRFAM: methylated-DNA--protein-cysteine methyltransferase; PFAM: Methylated-DNA-[protein]-cysteine S-methyltransferase DNA binding; KEGG: ecp:ECP_2256 ADA regulatory protein.
 
   
 0.474
cmk
KEGG: rrs:RoseRS_0324 cytidylate kinase; TIGRFAM: cytidylate kinase; PFAM: cytidylate kinase region.
  
    0.466
Caur_0610
DNA repair protein RecN; May be involved in recombinational repair of damaged DNA.
     
 0.465
pheT
KEGG: rrs:RoseRS_1038 phenylalanyl-tRNA synthetase, beta subunit; TIGRFAM: phenylalanyl-tRNA synthetase, beta subunit.
 
 
   0.449
polA
DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 3'-5' and 5'-3' exonuclease activity.
     
 0.440
sat-2
Sulfate adenylyltransferase; Catalyzes the synthesis of activated sulfate. Belongs to the sulfate adenylyltransferase family.
  
   0.430
Caur_0590
PFAM: class II aldolase/adducin family protein; KEGG: aba:Acid345_4482 class II aldolase/adducin-like.
  
  
 0.414
Your Current Organism:
Chloroflexus aurantiacus
NCBI taxonomy Id: 324602
Other names: C. aurantiacus J-10-fl, Chloroflexus aurantiacus ATCC 29366, Chloroflexus aurantiacus DSM 635, Chloroflexus aurantiacus J-10-fl, Chloroflexus aurantiacus str. J-10-fl, Chloroflexus aurantiacus strain J-10-fl
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