STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Caur_3207PFAM: NUDIX hydrolase; KEGG: rca:Rcas_0219 NUDIX hydrolase; Belongs to the Nudix hydrolase family. (157 aa)    
Predicted Functional Partners:
pyrC-2
Dihydroorotase, homodimeric type; Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.
    
   0.660
Caur_0446
PFAM: NUDIX hydrolase; KEGG: rrs:RoseRS_3464 NUDIX hydrolase; Belongs to the Nudix hydrolase family.
 
     0.587
Caur_2026
TIGRFAM: HAD-superfamily hydrolase, subfamily IIA; HAD-superfamily hydrolase, subfamily IA, variant 3; PFAM: Haloacid dehalogenase domain protein hydrolase; KEGG: rrs:RoseRS_1310 HAD-superfamily hydrolase, subfamily IIA; Belongs to the HAD-like hydrolase superfamily.
      0.503
cmk
KEGG: rrs:RoseRS_0324 cytidylate kinase; TIGRFAM: cytidylate kinase; PFAM: cytidylate kinase region.
  
    0.490
Caur_1407
TIGRFAM: methylated-DNA--protein-cysteine methyltransferase; PFAM: Methylated-DNA-[protein]-cysteine S-methyltransferase DNA binding; KEGG: ecp:ECP_2256 ADA regulatory protein.
 
   
 0.466
sat-2
Sulfate adenylyltransferase; Catalyzes the synthesis of activated sulfate. Belongs to the sulfate adenylyltransferase family.
  
   0.431
pheT
KEGG: rrs:RoseRS_1038 phenylalanyl-tRNA synthetase, beta subunit; TIGRFAM: phenylalanyl-tRNA synthetase, beta subunit.
 
 
   0.414
lspA
Lipoprotein signal peptidase; This protein specifically catalyzes the removal of signal peptides from prolipoproteins; Belongs to the peptidase A8 family.
  
  
 0.400
lspA-2
Lipoprotein signal peptidase; This protein specifically catalyzes the removal of signal peptides from prolipoproteins; Belongs to the peptidase A8 family.
  
  
 0.400
Your Current Organism:
Chloroflexus aurantiacus
NCBI taxonomy Id: 324602
Other names: C. aurantiacus J-10-fl, Chloroflexus aurantiacus ATCC 29366, Chloroflexus aurantiacus DSM 635, Chloroflexus aurantiacus J-10-fl, Chloroflexus aurantiacus str. J-10-fl, Chloroflexus aurantiacus strain J-10-fl
Server load: low (16%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.