Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
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Score
Caur_3389PFAM: heat shock protein DnaJ domain protein; KEGG: rca:Rcas_0258 heat shock protein DnaJ domain protein. (408 aa)    
Predicted Functional Partners:
htpG
Heat shock protein Hsp90; Molecular chaperone. Has ATPase activity.
  
 0.937
dnaK
Chaperone protein DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family.
  
 0.904
dnaK-2
Chaperone protein DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family.
  
 0.904
grpE
GrpE protein; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent i [...]
  
 
 0.885
Caur_0253
Hypothetical protein; KEGG: rca:Rcas_2219 putative FHA domain containing protein.
  
 
 
 0.873
Caur_1185
PFAM: Respiratory-chain NADH dehydrogenase domain 51 kDa subunit; KEGG: rrs:RoseRS_3542 NADH dehydrogenase (quinone).
   
  0.869
Caur_0613
PFAM: AMP-dependent synthetase and ligase; Enoyl-CoA hydratase/isomerase; Alcohol dehydrogenase GroES domain protein; KEGG: rrs:RoseRS_3202 AMP-dependent synthetase and ligase.
 
 
 0.856
Caur_0713
PFAM: Tetratricopeptide TPR_4; KEGG: rca:Rcas_2727 glycosyl transferase family 39.
  
 
  0.779
rplQ
PFAM: ribosomal protein L17; KEGG: rrs:RoseRS_1157 ribosomal protein L17.
 
 
 0.764
Caur_0695
PFAM: TPR repeat-containing protein; Tetratricopeptide TPR_4; Tetratricopeptide TPR_2 repeat protein; SMART: Tetratricopeptide domain protein; KEGG: rrs:RoseRS_0774 TPR repeat-containing protein.
  
 
  0.758
Your Current Organism:
Chloroflexus aurantiacus
NCBI taxonomy Id: 324602
Other names: C. aurantiacus J-10-fl, Chloroflexus aurantiacus ATCC 29366, Chloroflexus aurantiacus DSM 635, Chloroflexus aurantiacus J-10-fl, Chloroflexus aurantiacus str. J-10-fl, Chloroflexus aurantiacus strain J-10-fl
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