Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
Caur_3473PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; KEGG: rrs:RoseRS_3876 multi-sensor hybrid histidine kinase. (318 aa)    
Predicted Functional Partners:
Caur_0031
TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain containing protein; response regulator receiver; KEGG: rca:Rcas_3221 response regulator receiver modulated diguanylate cyclase.
   0.960
Caur_3058
TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain containing protein; response regulator receiver; KEGG: hha:Hhal_0365 response regulator receiver modulated diguanylate cyclase.
   0.958
Caur_2001
PFAM: response regulator receiver; transcriptional regulator domain protein; KEGG: rca:Rcas_4344 two component transcriptional regulator, winged helix family.
 
   0.952
Caur_0465
PFAM: response regulator receiver; ATP-binding region ATPase domain protein; KEGG: rca:Rcas_3883 multi-sensor hybrid histidine kinase.
 
 
 0.951
Caur_3514
TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain containing protein; GAF domain protein; KEGG: xcv:XCV2971 putative sensor protein.
 
  
 0.926
Caur_1559
PAS sensor protein; KEGG: rrs:RoseRS_3536 putative PAS/PAC sensor protein; TIGRFAM: PAS sensor protein; PFAM: Sulfate transporter/antisigma-factor antagonist STAS; PAS fold-3 domain protein; PAS fold-4 domain protein; PAS fold domain protein; SMART: PAS domain containing protein; PAC repeat-containing protein.
 
 0.919
Caur_0102
PAS sensor protein; KEGG: ppd:Ppro_2908 multi-sensor hybrid histidine kinase; TIGRFAM: PAS sensor protein; PFAM: response regulator receiver; ATP-binding region ATPase domain protein; histidine kinase A domain protein; PAS fold-3 domain protein; PAS fold-4 domain protein; PAS fold domain protein; SMART: PAS domain containing protein; PAC repeat-containing protein.
 
 
 0.895
Caur_3185
PFAM: Sulfate transporter/antisigma-factor antagonist STAS; PAS fold-4 domain protein; KEGG: rca:Rcas_2373 putative PAS/PAC sensor protein.
 
 
 0.886
Caur_2069
PFAM: response regulator receiver; KEGG: reh:H16_B2354 signal transduction histidine kinase containing two receiver domains (hybrid).
 
 
 0.877
Caur_3090
KEGG: dge:Dgeo_1999 metal dependent phosphohydrolase; TIGRFAM: metal dependent phophohydrolase; PFAM: response regulator receiver; metal-dependent phosphohydrolase HD sub domain; SMART: metal-dependent phosphohydrolase HD region.
 
 0.873
Your Current Organism:
Chloroflexus aurantiacus
NCBI taxonomy Id: 324602
Other names: C. aurantiacus J-10-fl, Chloroflexus aurantiacus ATCC 29366, Chloroflexus aurantiacus DSM 635, Chloroflexus aurantiacus J-10-fl, Chloroflexus aurantiacus str. J-10-fl, Chloroflexus aurantiacus strain J-10-fl
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