Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
RadCPFAM: DNA repair protein RadC; KEGG: rca:Rcas_0037 DNA repair protein RadC; Belongs to the UPF0758 family. (229 aa)    
Predicted Functional Partners:
Caur_1623
Maf protein; Nucleoside triphosphate pyrophosphatase that hydrolyzes dTTP and UTP. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.
 
  
 0.906
Caur_0115
Rod shape-determining protein MreC; Involved in formation and maintenance of cell shape.
  
  
 0.872
Caur_1845
KEGG: rrs:RoseRS_1875 amidophosphoribosyltransferase-like protein.
 
    0.787
fdhD
Formate dehydrogenase family accessory protein FdhD; Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH. Belongs to the FdhD family.
     
 0.683
mutS
DNA mismatch repair protein MutS; This protein is involved in the repair of mismatches in DNA. It is possible that it carries out the mismatch recognition step. This protein has a weak ATPase activity.
 
   
 0.638
mutL
DNA mismatch repair protein MutL; This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex.
 
   
 0.632
Caur_3274
PAS sensor protein; KEGG: sfu:Sfum_0942 multi-sensor signal transduction histidine kinase; TIGRFAM: PAS sensor protein; PFAM: PAS fold-4 domain protein; PAS fold domain protein; SMART: PAC repeat-containing protein.
  
    0.621
Caur_3534
Diguanylate cyclase; KEGG: ava:Ava_2710 putative diguanylate cyclase/phosphodiesterase (GGDEF & EAL domains) with PAS/PAC sensor(s); TIGRFAM: PAS sensor protein; diguanylate cyclase; PFAM: GGDEF domain containing protein; EAL domain protein; response regulator receiver; PAS fold-3 domain protein; PAS fold-4 domain protein; PAS fold domain protein; SMART: PAS domain containing protein; PAC repeat-containing protein.
  
    0.620
Caur_3602
PFAM: UspA domain protein; KEGG: tth:TTC1218 transcriptional regulator.
       0.568
Caur_2622
PFAM: ComEC/Rec2-related protein; KEGG: rrs:RoseRS_1609 ComEC/Rec2-related protein.
 
  
 0.559
Your Current Organism:
Chloroflexus aurantiacus
NCBI taxonomy Id: 324602
Other names: C. aurantiacus J-10-fl, Chloroflexus aurantiacus ATCC 29366, Chloroflexus aurantiacus DSM 635, Chloroflexus aurantiacus J-10-fl, Chloroflexus aurantiacus str. J-10-fl, Chloroflexus aurantiacus strain J-10-fl
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