STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
WacUncharacterized protein. (94 aa)    
Predicted Functional Partners:
Leo1
LEO1 homolog, Paf1/RNA polymerase II complex component.
   
 
 0.974
ENSXCOP00000011879
Small nuclear ribonucleoprotein 70 (U1).
   
 
 0.826
cdc5l
CDC5 cell division cycle 5-like (S. pombe).
   
 
 0.821
u2af2
U2 snRNP auxiliary factor large subunit; Necessary for the splicing of pre-mRNA. Belongs to the splicing factor SR family.
    
 
 0.768
SART1
Spliceosome associated factor 1, recruiter of U4/U6.U5 tri-snRNP.
   
   0.729
ENSXCOP00000012253
Small nuclear ribonucleoprotein E; Associated with the spliceosome snRNP U1, U2, U4/U6 and U5. Belongs to the snRNP Sm proteins family.
    
 
 0.729
SNRPC
U1 small nuclear ribonucleoprotein C; Component of the spliceosomal U1 snRNP, which is essential for recognition of the pre-mRNA 5' splice-site and the subsequent assembly of the spliceosome. SNRPC/U1-C is directly involved in initial 5' splice-site recognition for both constitutive and regulated alternative splicing. The interaction with the 5' splice-site seems to precede base-pairing between the pre-mRNA and the U1 snRNA. Stimulates commitment or early (E) complex formation by stabilizing the base pairing of the 5' end of the U1 snRNA and the 5' splice-site region.
    
 
 0.723
ENSXCOP00000005314
DEAD (Asp-Glu-Ala-Asp) box polypeptide 46.
   
 
 0.695
ENSXCOP00000011827
Splicing factor 3b, subunit 2.
   
 
 0.686
ENSXCOP00000002801
RNA binding motif protein 25b.
   
 
 0.678
Your Current Organism:
Xiphophorus couchianus
NCBI taxonomy Id: 32473
Other names: Limia couchiana, Monterrey platyfish, X. couchianus
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.