STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Lig4DNA ligase. (908 aa)    
Predicted Functional Partners:
ENSXCOP00000022376
Uncharacterized protein.
    
 0.996
ENSXCOP00000001771
X-ray repair complementing defective repair in Chinese hamster cells 5.
   
 0.985
Xrcc6
X-ray repair complementing defective repair in Chinese hamster cells 6.
   
 0.984
Nhej1
Nonhomologous end-joining factor 1.
    
 0.984
pcna
Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family.
   
 0.957
ENSXCOP00000010301
X-ray repair complementing defective repair in Chinese hamster cells 1.
   
 0.935
Dclre1a
DNA cross-link repair 1A (PSO2 homolog, S. cerevisiae).
  
 0.881
ENSXCOP00000021731
X-ray repair complementing defective repair in Chinese hamster cells 4.
    
 0.867
Dntt
BRCT domain-containing protein; Belongs to the DNA polymerase type-X family.
  
 0.843
ENSXCOP00000016510
DNA polymerase; DNA polymerase that functions in several pathways of DNA repair. Involved in base excision repair (BER) responsible for repair of lesions that give rise to abasic (AP) sites in DNA. Also contributes to DNA double-strand break repair by non-homologous end joining and homologous recombination. Has both template-dependent and template- independent (terminal transferase) DNA polymerase activities. Has also a 5'-deoxyribose-5-phosphate lyase (dRP lyase) activity.
  
 0.835
Your Current Organism:
Xiphophorus couchianus
NCBI taxonomy Id: 32473
Other names: Limia couchiana, Monterrey platyfish, X. couchianus
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