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Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
LGAS_0286Type II secretory pathway, prepilin signal peptidase PulO related peptidase. (225 aa)    
Predicted Functional Partners:
LGAS_1275
Type II secretory pathway/competence component, ATPase.
 
 
 0.848
LGAS_1174
Predicted hydrolase (metallo-beta-lactamase superfamily).
  
  
 0.846
LGAS_1274
Type II secretory pathway/competence component.
 
  
 0.795
LGAS_1273
Competence protein ComGC.
  
  
 0.768
LGAS_0915
Rossmann fold nucleotide-binding protein for DNA uptake.
  
  
 0.758
LGAS_1175
DNA uptake protein related DNA-binding protein.
  
  
 0.737
rpsL
SSU ribosomal protein S12P; Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
     
 0.656
LGAS_1334
Superfamily II DNA/RNA helicase required for DNA uptake (late competence protein).
   
  
 0.626
rpsG
SSU ribosomal protein S7P; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA; Belongs to the universal ribosomal protein uS7 family.
       0.607
LGAS_1272
Hypothetical protein.
  
  
 0.590
Your Current Organism:
Lactobacillus gasseri
NCBI taxonomy Id: 324831
Other names: L. gasseri ATCC 33323 = JCM 1131, Lactobacillus gasseri ATCC 33323, Lactobacillus gasseri ATCC 33323 = JCM 1131, Lactobacillus gasseri DSM 20243, Lactobacillus gasseri NCDO 2233
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