| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| LGAS_0093 | LGAS_0829 | LGAS_0093 | LGAS_0829 | Phosphatidylserine/phosphatidylglycerophosphate/ cardiolipin synthase related enzyme; Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol. | Phosphatidylserine/phosphatidylglycerophosphate/ cardiolipin synthase related enzyme; Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol. | 0.905 |
| LGAS_0093 | LGAS_1174 | LGAS_0093 | LGAS_1174 | Phosphatidylserine/phosphatidylglycerophosphate/ cardiolipin synthase related enzyme; Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol. | Predicted hydrolase (metallo-beta-lactamase superfamily). | 0.445 |
| LGAS_0093 | LGAS_1339 | LGAS_0093 | LGAS_1339 | Phosphatidylserine/phosphatidylglycerophosphate/ cardiolipin synthase related enzyme; Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol. | CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase; Belongs to the CDP-alcohol phosphatidyltransferase class-I family. | 0.419 |
| LGAS_0093 | LGAS_1768 | LGAS_0093 | LGAS_1768 | Phosphatidylserine/phosphatidylglycerophosphate/ cardiolipin synthase related enzyme; Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol. | Membrane domain of membrane-anchored glycerophosphoryl diester phosphodiesterase. | 0.419 |
| LGAS_0829 | LGAS_0093 | LGAS_0829 | LGAS_0093 | Phosphatidylserine/phosphatidylglycerophosphate/ cardiolipin synthase related enzyme; Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol. | Phosphatidylserine/phosphatidylglycerophosphate/ cardiolipin synthase related enzyme; Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol. | 0.905 |
| LGAS_0829 | LGAS_0831 | LGAS_0829 | LGAS_0831 | Phosphatidylserine/phosphatidylglycerophosphate/ cardiolipin synthase related enzyme; Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol. | Dihydrofolate reductase; Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis. | 0.481 |
| LGAS_0829 | LGAS_1174 | LGAS_0829 | LGAS_1174 | Phosphatidylserine/phosphatidylglycerophosphate/ cardiolipin synthase related enzyme; Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol. | Predicted hydrolase (metallo-beta-lactamase superfamily). | 0.445 |
| LGAS_0829 | LGAS_1339 | LGAS_0829 | LGAS_1339 | Phosphatidylserine/phosphatidylglycerophosphate/ cardiolipin synthase related enzyme; Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol. | CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase; Belongs to the CDP-alcohol phosphatidyltransferase class-I family. | 0.419 |
| LGAS_0829 | LGAS_1768 | LGAS_0829 | LGAS_1768 | Phosphatidylserine/phosphatidylglycerophosphate/ cardiolipin synthase related enzyme; Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol. | Membrane domain of membrane-anchored glycerophosphoryl diester phosphodiesterase. | 0.419 |
| LGAS_0829 | thyA | LGAS_0829 | LGAS_0830 | Phosphatidylserine/phosphatidylglycerophosphate/ cardiolipin synthase related enzyme; Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol. | Thymidylate synthase; Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by- product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis. | 0.594 |
| LGAS_0831 | LGAS_0829 | LGAS_0831 | LGAS_0829 | Dihydrofolate reductase; Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis. | Phosphatidylserine/phosphatidylglycerophosphate/ cardiolipin synthase related enzyme; Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol. | 0.481 |
| LGAS_0831 | LGAS_1339 | LGAS_0831 | LGAS_1339 | Dihydrofolate reductase; Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis. | CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase; Belongs to the CDP-alcohol phosphatidyltransferase class-I family. | 0.415 |
| LGAS_0831 | thyA | LGAS_0831 | LGAS_0830 | Dihydrofolate reductase; Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis. | Thymidylate synthase; Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by- product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis. | 0.999 |
| LGAS_1174 | LGAS_0093 | LGAS_1174 | LGAS_0093 | Predicted hydrolase (metallo-beta-lactamase superfamily). | Phosphatidylserine/phosphatidylglycerophosphate/ cardiolipin synthase related enzyme; Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol. | 0.445 |
| LGAS_1174 | LGAS_0829 | LGAS_1174 | LGAS_0829 | Predicted hydrolase (metallo-beta-lactamase superfamily). | Phosphatidylserine/phosphatidylglycerophosphate/ cardiolipin synthase related enzyme; Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol. | 0.445 |
| LGAS_1174 | LGAS_1339 | LGAS_1174 | LGAS_1339 | Predicted hydrolase (metallo-beta-lactamase superfamily). | CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase; Belongs to the CDP-alcohol phosphatidyltransferase class-I family. | 0.432 |
| LGAS_1339 | LGAS_0093 | LGAS_1339 | LGAS_0093 | CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase; Belongs to the CDP-alcohol phosphatidyltransferase class-I family. | Phosphatidylserine/phosphatidylglycerophosphate/ cardiolipin synthase related enzyme; Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol. | 0.419 |
| LGAS_1339 | LGAS_0829 | LGAS_1339 | LGAS_0829 | CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase; Belongs to the CDP-alcohol phosphatidyltransferase class-I family. | Phosphatidylserine/phosphatidylglycerophosphate/ cardiolipin synthase related enzyme; Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol. | 0.419 |
| LGAS_1339 | LGAS_0831 | LGAS_1339 | LGAS_0831 | CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase; Belongs to the CDP-alcohol phosphatidyltransferase class-I family. | Dihydrofolate reductase; Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis. | 0.415 |
| LGAS_1339 | LGAS_1174 | LGAS_1339 | LGAS_1174 | CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase; Belongs to the CDP-alcohol phosphatidyltransferase class-I family. | Predicted hydrolase (metallo-beta-lactamase superfamily). | 0.432 |