STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
LGAS_1357Competence protein. (312 aa)    
Predicted Functional Partners:
LGAS_1358
Negative regulator of genetic competence, sporulation and motility; Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis; Belongs to the MecA family.
 
   
 0.859
LGAS_1174
Predicted hydrolase (metallo-beta-lactamase superfamily).
 
  
 0.717
LGAS_1274
Type II secretory pathway/competence component.
  
  
 0.698
LGAS_1442
Predicted ABC-type exoprotein transport system, permease component.
 
     0.656
spxA
Arsenate reductase related protein, glutaredoxin family; Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development- promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress. Belongs to the ArsC family. Spx subfamily.
     
 0.653
divIB
Cell division protein FtsQ; Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex; Belongs to the FtsQ/DivIB family. DivIB subfamily.
 
     0.614
LGAS_1417
Replicative DNA helicase loader DnaB.
  
     0.576
LGAS_1627
Predicted membrane protein.
  
     0.568
LGAS_0108
Predicted transcriptional regulator.
  
     0.567
rexB
ATP-dependent nuclease, subunit B; ATP-dependent DNA helicase.
  
   
 0.563
Your Current Organism:
Lactobacillus gasseri
NCBI taxonomy Id: 324831
Other names: L. gasseri ATCC 33323 = JCM 1131, Lactobacillus gasseri ATCC 33323, Lactobacillus gasseri ATCC 33323 = JCM 1131, Lactobacillus gasseri DSM 20243, Lactobacillus gasseri NCDO 2233
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