Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
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[Homology]
Score
LGAS_1734Signal transduction histidine kinase. (381 aa)    
Predicted Functional Partners:
LGAS_1735
DNA-binding response regulator, OmpR family (Rec-wHTH domains).
 
 0.984
LGAS_0064
DNA-binding response regulator, OmpR family (Rec-wHTH domains).
 
 0.888
LGAS_1261
DNA-binding response regulator, OmpR family (Rec-wHTH domains).
 
 0.885
LGAS_1398
DNA-binding response regulator, OmpR family (Rec-wHTH domains).
 
 0.879
LGAS_0710
DNA-binding response regulator, OmpR family (Rec-wHTH domains).
 
 0.854
murE
UDP-N-acetylmuramyl tripeptide synthase; Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan.
  
  
 0.709
LGAS_1732
Aspartate racemase; Belongs to the aspartate/glutamate racemases family.
       0.684
LGAS_0067
Hypothetical protein.
 
  
 0.581
LGAS_0066
Hypothetical protein.
 
  
 0.565
LGAS_0068
Metal-dependent hydrolase of the beta-lactamase superfamily I.
  
  
 0.493
Your Current Organism:
Lactobacillus gasseri
NCBI taxonomy Id: 324831
Other names: L. gasseri ATCC 33323 = JCM 1131, Lactobacillus gasseri ATCC 33323, Lactobacillus gasseri ATCC 33323 = JCM 1131, Lactobacillus gasseri DSM 20243, Lactobacillus gasseri NCDO 2233
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