node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
LGAS_1847 | LGAS_1848 | LGAS_1847 | LGAS_1848 | ABC-type phosphate/phosphonate transport system, periplasmic component. | Nucleoside-binding protein. | 0.535 |
LGAS_1848 | LGAS_1847 | LGAS_1848 | LGAS_1847 | Nucleoside-binding protein. | ABC-type phosphate/phosphonate transport system, periplasmic component. | 0.535 |
LGAS_1848 | LGAS_1849 | LGAS_1848 | LGAS_1849 | Nucleoside-binding protein. | Prolyl aminopeptidase; Releases the N-terminal proline from various substrates. Belongs to the peptidase S33 family. | 0.491 |
LGAS_1848 | guaA | LGAS_1848 | LGAS_0231 | Nucleoside-binding protein. | GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP. | 0.688 |
LGAS_1848 | guaC | LGAS_1848 | LGAS_0389 | Nucleoside-binding protein. | IMP dehydrogenase/GMP reductase; Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides; Belongs to the IMPDH/GMPR family. GuaC type 2 subfamily. | 0.437 |
LGAS_1848 | purA | LGAS_1848 | LGAS_0390 | Nucleoside-binding protein. | Adenylosuccinate synthetase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family. | 0.467 |
LGAS_1849 | LGAS_1848 | LGAS_1849 | LGAS_1848 | Prolyl aminopeptidase; Releases the N-terminal proline from various substrates. Belongs to the peptidase S33 family. | Nucleoside-binding protein. | 0.491 |
guaA | LGAS_1848 | LGAS_0231 | LGAS_1848 | GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP. | Nucleoside-binding protein. | 0.688 |
guaA | guaC | LGAS_0231 | LGAS_0389 | GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP. | IMP dehydrogenase/GMP reductase; Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides; Belongs to the IMPDH/GMPR family. GuaC type 2 subfamily. | 0.998 |
guaA | purA | LGAS_0231 | LGAS_0390 | GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP. | Adenylosuccinate synthetase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family. | 0.924 |
guaC | LGAS_1848 | LGAS_0389 | LGAS_1848 | IMP dehydrogenase/GMP reductase; Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides; Belongs to the IMPDH/GMPR family. GuaC type 2 subfamily. | Nucleoside-binding protein. | 0.437 |
guaC | guaA | LGAS_0389 | LGAS_0231 | IMP dehydrogenase/GMP reductase; Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides; Belongs to the IMPDH/GMPR family. GuaC type 2 subfamily. | GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP. | 0.998 |
guaC | purA | LGAS_0389 | LGAS_0390 | IMP dehydrogenase/GMP reductase; Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides; Belongs to the IMPDH/GMPR family. GuaC type 2 subfamily. | Adenylosuccinate synthetase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family. | 0.999 |
purA | LGAS_1848 | LGAS_0390 | LGAS_1848 | Adenylosuccinate synthetase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family. | Nucleoside-binding protein. | 0.467 |
purA | guaA | LGAS_0390 | LGAS_0231 | Adenylosuccinate synthetase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family. | GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP. | 0.924 |
purA | guaC | LGAS_0390 | LGAS_0389 | Adenylosuccinate synthetase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family. | IMP dehydrogenase/GMP reductase; Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides; Belongs to the IMPDH/GMPR family. GuaC type 2 subfamily. | 0.999 |