STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Ppha_0004KEGG: plt:Plut_0003 hypothetical protein. (97 aa)    
Predicted Functional Partners:
recF
DNA replication and repair protein RecF; The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP.
 
  
 0.843
Ppha_0002
DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...]
     
 0.790
Ppha_2165
PFAM: phosphatidate cytidylyltransferase; protein of unknown function DUF92 transmembrane; KEGG: cph:Cpha266_0855 protein of unknown function DUF92, transmembrane.
  
     0.459
dnaA
Chromosomal replication initiator protein DnaA; Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'- TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids. Belongs to the DnaA family.
       0.458
Ppha_2548
KEGG: pvi:Cvib_0351 hypothetical protein.
 
     0.446
Ppha_2603
KEGG: cph:Cpha266_0345 hypothetical protein.
  
     0.441
Ppha_0723
PFAM: metallophosphoesterase; KEGG: plt:Plut_1594 hypothetical protein.
  
     0.435
Ppha_1876
PFAM: ferrochelatase; KEGG: cph:Cpha266_0958 ferrochelatase; Belongs to the ferrochelatase family.
  
     0.433
Ppha_2881
KEGG: cph:Cpha266_2704 putative lipoprotein.
  
     0.425
Ppha_0828
KEGG: cph:Cpha266_1942 hypothetical protein.
  
     0.410
Your Current Organism:
Pelodictyon phaeoclathratiforme
NCBI taxonomy Id: 324925
Other names: P. phaeoclathratiforme BU-1, Pelodictyon phaeoclathratiforme BU-1, Pelodictyon phaeoclathratiforme DSM 5477, Pelodictyon phaeoclathratiforme str. BU-1, Pelodictyon phaeoclathratiforme strain BU-1
Server load: low (18%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.