STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Ppha_0017PFAM: protein of unknown function UPF0102; KEGG: cph:Cpha266_0037 hypothetical protein; Belongs to the UPF0102 family. (128 aa)    
Predicted Functional Partners:
rnhB
Ribonuclease H; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids; Belongs to the RNase HII family.
       0.795
Ppha_0672
Mg chelatase, subunit ChlI; KEGG: cch:Cag_1757 Mg chelatase-related protein; TIGRFAM: Mg chelatase, subunit ChlI; PFAM: magnesium chelatase ChlI subunit; ATPase associated with various cellular activities AAA_5; SMART: AAA ATPase.
 
  
 0.794
Ppha_0336
PFAM: phosphoribosyltransferase; KEGG: plt:Plut_0226 competence protein.
 
    0.719
Ppha_0412
TIGRFAM: DNA protecting protein DprA; PFAM: SMF family protein; KEGG: cph:Cpha266_0383 DNA protecting protein DprA.
 
    0.690
Ppha_0019
PFAM: conserved hypothetical protein; KEGG: cph:Cpha266_1465 hypothetical protein.
       0.568
gyrB
DNA gyrase, B subunit; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
       0.566
Ppha_1646
PFAM: ComEC/Rec2-related protein; KEGG: cph:Cpha266_1722 ComEC/Rec2-related protein.
  
    0.505
Ppha_0020
PFAM: HicB family protein; KEGG: cph:Cpha266_2191 HicB family protein.
       0.422
Ppha_0021
HicA protein; KEGG: cph:Cpha266_2192 HicA protein.
       0.422
Your Current Organism:
Pelodictyon phaeoclathratiforme
NCBI taxonomy Id: 324925
Other names: P. phaeoclathratiforme BU-1, Pelodictyon phaeoclathratiforme BU-1, Pelodictyon phaeoclathratiforme DSM 5477, Pelodictyon phaeoclathratiforme str. BU-1, Pelodictyon phaeoclathratiforme strain BU-1
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