Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
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[Homology]
Score
Ppha_0254TIGRFAM: phosphocarrier, HPr family; PFAM: phosphocarrier HPr protein; KEGG: cph:Cpha266_2443 phosphotransferase system, phosphocarrier protein HPr. (88 aa)    
Predicted Functional Partners:
Ppha_2607
Phosphoenolpyruvate-protein phosphotransferase; General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr).
 
 0.997
Ppha_0392
Putative PTS IIA-like nitrogen-regulatory protein PtsN; PFAM: phosphoenolpyruvate-dependent sugar phosphotransferase system EIIA 2; KEGG: plt:Plut_1787 putative PTS IIA-like nitrogen-regulatory protein PtsN.
 
 
 0.967
hprK
HPr kinase; Catalyzes the ATP- as well as the pyrophosphate-dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK/P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P-Ser-HPr).
 
 
 
 0.830
obg
GTP-binding protein Obg/CgtA; An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control. Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.
       0.714
Ppha_0253
PFAM: GCN5-related N-acetyltransferase; KEGG: plt:Plut_0166 acetyltransferase; Belongs to the acetyltransferase family.
       0.682
Ppha_0256
PFAM: glycosyl transferase family 2; KEGG: plt:Plut_0169 glycosyl transferase.
       0.610
Ppha_0255
PFAM: glycosyl transferase group 1; KEGG: cph:Cpha266_2442 glycosyl transferase, group 1.
       0.593
Ppha_0259
PFAM: polysaccharide biosynthesis protein; KEGG: cch:Cag_1862 polysaccharide efflux transporter, putative.
  
    0.568
Ppha_0260
KEGG: cch:Cag_1857 hypothetical protein.
       0.544
Ppha_0257
KEGG: cch:Cag_1865 hypothetical protein.
       0.532
Your Current Organism:
Pelodictyon phaeoclathratiforme
NCBI taxonomy Id: 324925
Other names: P. phaeoclathratiforme BU-1, Pelodictyon phaeoclathratiforme BU-1, Pelodictyon phaeoclathratiforme DSM 5477, Pelodictyon phaeoclathratiforme str. BU-1, Pelodictyon phaeoclathratiforme strain BU-1
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