STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
fniIsopentenyl-diphosphate delta-isomerase, type 2; Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP). (357 aa)    
Predicted Functional Partners:
Ppha_0413
PFAM: Polyprenyl synthetase; KEGG: cph:Cpha266_0384 polyprenyl synthetase; Belongs to the FPP/GGPP synthase family.
 
 
 0.984
ispH
Hydroxymethylbutenyl pyrophosphate reductase; Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis. Belongs to the IspH family.
    
 0.923
Ppha_1652
FAD linked oxidase domain protein; PFAM: protein of unknown function DUF224 cysteine-rich region domain protein; FAD linked oxidase domain protein; KEGG: cch:Cag_0799 oxidoreductase, FAD-binding.
  
 0.777
Ppha_0412
TIGRFAM: DNA protecting protein DprA; PFAM: SMF family protein; KEGG: cph:Cpha266_0383 DNA protecting protein DprA.
       0.756
Ppha_0863
D-lactate dehydrogenase (cytochrome); PFAM: FAD linked oxidase domain protein; KEGG: pvi:Cvib_1206 D-lactate dehydrogenase (cytochrome).
  
 0.591
Ppha_0695
PFAM: 4Fe-4S ferredoxin iron-sulfur binding domain protein; pyruvate ferredoxin/flavodoxin oxidoreductase; pyruvate flavodoxin/ferredoxin oxidoreductase domain protein; KEGG: cph:Cpha266_0571 pyruvate flavodoxin/ferredoxin oxidoreductase domain protein.
     
 0.537
Ppha_0217
Serine--glyoxylate transaminase; PFAM: aminotransferase class V; KEGG: cph:Cpha266_2460 serine--glyoxylate transaminase.
  
 0.514
guaA
GMP synthase, large subunit; Catalyzes the synthesis of GMP from XMP.
  
  
 0.464
Ppha_1069
FHA domain containing protein; PFAM: Forkhead-associated protein; KEGG: bth:BT_2774 putative adenylate cyclase.
   
 
  0.434
Your Current Organism:
Pelodictyon phaeoclathratiforme
NCBI taxonomy Id: 324925
Other names: P. phaeoclathratiforme BU-1, Pelodictyon phaeoclathratiforme BU-1, Pelodictyon phaeoclathratiforme DSM 5477, Pelodictyon phaeoclathratiforme str. BU-1, Pelodictyon phaeoclathratiforme strain BU-1
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