STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Ppha_0537KEGG: aeh:Mlg_2331 hypothetical protein. (426 aa)    
Predicted Functional Partners:
Ppha_0538
TIGRFAM: methyltransferase FkbM family; KEGG: ava:Ava_1043 methyltransferase FkbM.
       0.773
Ppha_0533
PFAM: oxidoreductase domain protein; KEGG: pmf:P9303_01161 hypothetical protein.
       0.693
Ppha_0534
PFAM: acylneuraminate cytidylyltransferase; KEGG: dvl:Dvul_2588 N-acylneuraminate cytidylyltransferase.
       0.693
Ppha_0535
PFAM: short-chain dehydrogenase/reductase SDR; KEGG: nwi:Nwi_2393 short-chain dehydrogenase/reductase SDR.
       0.693
Ppha_0536
PFAM: transferase hexapeptide repeat containing protein; KEGG: vvy:VV0322 acetyltransferase.
       0.693
Ppha_0531
Histidine biosynthesis protein; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.
       0.665
hisH-2
Imidazole glycerol phosphate synthase, glutamine amidotransferase subunit; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.
       0.665
Ppha_0530
KEGG: lpc:LPC_2544 LPS biosynthesis protein, PseA-like protein.
       0.656
Ppha_0529
Nucleotidyl transferase; PFAM: CBS domain containing protein; Nucleotidyl transferase; KEGG: tdn:Tmden_0598 nucleotidyl transferase.
       0.647
Ppha_0524
PFAM: NAD-dependent epimerase/dehydratase; short-chain dehydrogenase/reductase SDR; 3-beta hydroxysteroid dehydrogenase/isomerase; polysaccharide biosynthesis protein CapD; dTDP-4-dehydrorhamnose reductase; Male sterility domain; KEGG: lic:LIC12176 UDP-glucose 4-epimerase.
       0.614
Your Current Organism:
Pelodictyon phaeoclathratiforme
NCBI taxonomy Id: 324925
Other names: P. phaeoclathratiforme BU-1, Pelodictyon phaeoclathratiforme BU-1, Pelodictyon phaeoclathratiforme DSM 5477, Pelodictyon phaeoclathratiforme str. BU-1, Pelodictyon phaeoclathratiforme strain BU-1
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