Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
Ppha_0538TIGRFAM: methyltransferase FkbM family; KEGG: ava:Ava_1043 methyltransferase FkbM. (228 aa)    
Predicted Functional Partners:
Ppha_0537
KEGG: aeh:Mlg_2331 hypothetical protein.
       0.773
Ppha_0533
PFAM: oxidoreductase domain protein; KEGG: pmf:P9303_01161 hypothetical protein.
 
 
   0.753
Ppha_0535
PFAM: short-chain dehydrogenase/reductase SDR; KEGG: nwi:Nwi_2393 short-chain dehydrogenase/reductase SDR.
  
   0.706
Ppha_0529
Nucleotidyl transferase; PFAM: CBS domain containing protein; Nucleotidyl transferase; KEGG: tdn:Tmden_0598 nucleotidyl transferase.
  
   0.701
Ppha_0534
PFAM: acylneuraminate cytidylyltransferase; KEGG: dvl:Dvul_2588 N-acylneuraminate cytidylyltransferase.
       0.693
Ppha_0536
PFAM: transferase hexapeptide repeat containing protein; KEGG: vvy:VV0322 acetyltransferase.
       0.693
Ppha_0531
Histidine biosynthesis protein; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.
       0.665
hisH-2
Imidazole glycerol phosphate synthase, glutamine amidotransferase subunit; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.
       0.665
Ppha_0530
KEGG: lpc:LPC_2544 LPS biosynthesis protein, PseA-like protein.
       0.656
Ppha_0523
PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: pvi:Cvib_0616 ABC transporter related.
 
 
  0.649
Your Current Organism:
Pelodictyon phaeoclathratiforme
NCBI taxonomy Id: 324925
Other names: P. phaeoclathratiforme BU-1, Pelodictyon phaeoclathratiforme BU-1, Pelodictyon phaeoclathratiforme DSM 5477, Pelodictyon phaeoclathratiforme str. BU-1, Pelodictyon phaeoclathratiforme strain BU-1
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