STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
gmdGDP-mannose 4,6-dehydratase; Catalyzes the conversion of GDP-D-mannose to GDP-4-dehydro-6- deoxy-D-mannose. (380 aa)    
Predicted Functional Partners:
fcl
NAD-dependent epimerase/dehydratase; Catalyzes the two-step NADP-dependent conversion of GDP-4- dehydro-6-deoxy-D-mannose to GDP-fucose, involving an epimerase and a reductase reaction.
 0.997
Ppha_2289
KEGG: cch:Cag_0518 mannose-1-phosphate guanylyltransferase/mannose-6-phosphate isomerase; TIGRFAM: mannose-1-phosphate guanylyltransferase/mannose-6-phosphate isomerase; PFAM: mannose-6-phosphate isomerase type II; Nucleotidyl transferase; Cupin 2 conserved barrel domain protein.
  
 
 0.954
Ppha_0319
PFAM: Nucleotidyl transferase; KEGG: cch:Cag_1821 mannose-1-phosphate guanylyltransferase, putative.
  
 
 0.920
Ppha_2761
PFAM: Nucleotidyl transferase; KEGG: cch:Cag_0193 mannose-1-phosphate guanylyltransferase, putative.
    
 0.903
gmd-2
GDP-mannose 4,6-dehydratase; Catalyzes the conversion of GDP-D-mannose to GDP-4-dehydro-6- deoxy-D-mannose.
  
  
 
0.900
Ppha_0569
PFAM: sugar transferase; KEGG: cph:Cpha266_2615 sugar transferase.
  
  
 0.871
Ppha_0568
PFAM: NAD-dependent epimerase/dehydratase; 3-beta hydroxysteroid dehydrogenase/isomerase; polysaccharide biosynthesis protein CapD; dTDP-4-dehydrorhamnose reductase; Male sterility domain; KEGG: cph:Cpha266_2616 NAD-dependent epimerase/dehydratase.
  
 
 0.744
Ppha_0567
PFAM: glycosyl transferase family 2; KEGG: rma:Rmag_0889 glycosyl transferase, family 2.
 
  
 0.723
Ppha_0566
PFAM: glycosyl transferase family 2; KEGG: bvu:BVU_2654 glycosyltransferase family 2.
  
  
 0.652
Ppha_0565
Hypothetical protein; KEGG: ret:RHE_CH03209 putative methyltransferase protein.
     
 0.634
Your Current Organism:
Pelodictyon phaeoclathratiforme
NCBI taxonomy Id: 324925
Other names: P. phaeoclathratiforme BU-1, Pelodictyon phaeoclathratiforme BU-1, Pelodictyon phaeoclathratiforme DSM 5477, Pelodictyon phaeoclathratiforme str. BU-1, Pelodictyon phaeoclathratiforme strain BU-1
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