| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| Ppha_0837 | Ppha_0839 | Ppha_0837 | Ppha_0839 | Hypothetical protein. | PFAM: Abortive infection protein; KEGG: cph:Cpha266_1934 abortive infection protein. | 0.438 |
| Ppha_0837 | queC | Ppha_0837 | Ppha_0838 | Hypothetical protein. | exsB protein; Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)). Belongs to the QueC family. | 0.438 |
| Ppha_0839 | Ppha_0837 | Ppha_0839 | Ppha_0837 | PFAM: Abortive infection protein; KEGG: cph:Cpha266_1934 abortive infection protein. | Hypothetical protein. | 0.438 |
| Ppha_0839 | Ppha_0841 | Ppha_0839 | Ppha_0841 | PFAM: Abortive infection protein; KEGG: cph:Cpha266_1934 abortive infection protein. | PFAM: glycosyl transferase family 2; KEGG: cph:Cpha266_1932 glycosyl transferase, family 2. | 0.692 |
| Ppha_0839 | queC | Ppha_0839 | Ppha_0838 | PFAM: Abortive infection protein; KEGG: cph:Cpha266_1934 abortive infection protein. | exsB protein; Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)). Belongs to the QueC family. | 0.787 |
| Ppha_0839 | trpA | Ppha_0839 | Ppha_0840 | PFAM: Abortive infection protein; KEGG: cph:Cpha266_1934 abortive infection protein. | Tryptophan synthase, alpha subunit; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family. | 0.687 |
| Ppha_0841 | Ppha_0839 | Ppha_0841 | Ppha_0839 | PFAM: glycosyl transferase family 2; KEGG: cph:Cpha266_1932 glycosyl transferase, family 2. | PFAM: Abortive infection protein; KEGG: cph:Cpha266_1934 abortive infection protein. | 0.692 |
| Ppha_0841 | queC | Ppha_0841 | Ppha_0838 | PFAM: glycosyl transferase family 2; KEGG: cph:Cpha266_1932 glycosyl transferase, family 2. | exsB protein; Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)). Belongs to the QueC family. | 0.680 |
| Ppha_0841 | trpA | Ppha_0841 | Ppha_0840 | PFAM: glycosyl transferase family 2; KEGG: cph:Cpha266_1932 glycosyl transferase, family 2. | Tryptophan synthase, alpha subunit; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family. | 0.808 |
| Ppha_0936 | Ppha_1857 | Ppha_0936 | Ppha_1857 | PFAM: 6-pyruvoyl tetrahydropterin synthase and hypothetical protein; KEGG: cph:Cpha266_1847 6-pyruvoyl tetrahydropterin synthase and hypothetical protein. | PFAM: 6-pyruvoyl tetrahydropterin synthase and hypothetical protein; KEGG: cch:Cag_0373 6-pyruvoyltetrahydropterin synthase. | 0.900 |
| Ppha_0936 | queC | Ppha_0936 | Ppha_0838 | PFAM: 6-pyruvoyl tetrahydropterin synthase and hypothetical protein; KEGG: cph:Cpha266_1847 6-pyruvoyl tetrahydropterin synthase and hypothetical protein. | exsB protein; Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)). Belongs to the QueC family. | 0.804 |
| Ppha_0936 | queE | Ppha_0936 | Ppha_2280 | PFAM: 6-pyruvoyl tetrahydropterin synthase and hypothetical protein; KEGG: cph:Cpha266_1847 6-pyruvoyl tetrahydropterin synthase and hypothetical protein. | Radical SAM domain protein; Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7- deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds. | 0.978 |
| Ppha_0936 | queF | Ppha_0936 | Ppha_0685 | PFAM: 6-pyruvoyl tetrahydropterin synthase and hypothetical protein; KEGG: cph:Cpha266_1847 6-pyruvoyl tetrahydropterin synthase and hypothetical protein. | 7-cyano-7-deazaguanine reductase; Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1). Belongs to the GTP cyclohydrolase I family. QueF type 1 subfamily. | 0.722 |
| Ppha_1857 | Ppha_0936 | Ppha_1857 | Ppha_0936 | PFAM: 6-pyruvoyl tetrahydropterin synthase and hypothetical protein; KEGG: cch:Cag_0373 6-pyruvoyltetrahydropterin synthase. | PFAM: 6-pyruvoyl tetrahydropterin synthase and hypothetical protein; KEGG: cph:Cpha266_1847 6-pyruvoyl tetrahydropterin synthase and hypothetical protein. | 0.900 |
| Ppha_1857 | queC | Ppha_1857 | Ppha_0838 | PFAM: 6-pyruvoyl tetrahydropterin synthase and hypothetical protein; KEGG: cch:Cag_0373 6-pyruvoyltetrahydropterin synthase. | exsB protein; Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)). Belongs to the QueC family. | 0.801 |
| Ppha_1857 | queE | Ppha_1857 | Ppha_2280 | PFAM: 6-pyruvoyl tetrahydropterin synthase and hypothetical protein; KEGG: cch:Cag_0373 6-pyruvoyltetrahydropterin synthase. | Radical SAM domain protein; Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7- deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds. | 0.975 |
| Ppha_1857 | queF | Ppha_1857 | Ppha_0685 | PFAM: 6-pyruvoyl tetrahydropterin synthase and hypothetical protein; KEGG: cch:Cag_0373 6-pyruvoyltetrahydropterin synthase. | 7-cyano-7-deazaguanine reductase; Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1). Belongs to the GTP cyclohydrolase I family. QueF type 1 subfamily. | 0.720 |
| Ppha_1890 | queC | Ppha_1890 | Ppha_0838 | Riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | exsB protein; Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)). Belongs to the QueC family. | 0.403 |
| Ppha_1890 | ribBA | Ppha_1890 | Ppha_0726 | Riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | 3,4-dihydroxy-2-butanone 4-phosphate synthase; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; In the N-terminal section; belongs to the DHBP synthase family. | 0.999 |
| queC | Ppha_0837 | Ppha_0838 | Ppha_0837 | exsB protein; Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)). Belongs to the QueC family. | Hypothetical protein. | 0.438 |