| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| Ppha_0928 | Ppha_1985 | Ppha_0928 | Ppha_1985 | Sun protein; Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA. | KEGG: plt:Plut_1351 PAS/PAC sensor hybrid histidine kinase; TIGRFAM: PAS sensor protein; PFAM: response regulator receiver; ATP-binding region ATPase domain protein; histidine kinase A domain protein; PAS fold-3 domain protein; PAS fold-4 domain protein; PAS fold domain protein; SMART: PAS domain containing protein; PAC repeat-containing protein. | 0.529 |
| Ppha_0928 | topA | Ppha_0928 | Ppha_2842 | Sun protein; Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA. | DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...] | 0.609 |
| Ppha_0928 | xerD | Ppha_0928 | Ppha_0927 | Sun protein; Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA. | Tyrosine recombinase XerD; Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC- XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids. | 0.790 |
| Ppha_1122 | xerD | Ppha_1122 | Ppha_0927 | PFAM: protein of unknown function DUF159; KEGG: cph:Cpha266_1054 protein of unknown function DUF159; Belongs to the SOS response-associated peptidase family. | Tyrosine recombinase XerD; Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC- XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids. | 0.510 |
| Ppha_1436 | Ppha_1985 | Ppha_1436 | Ppha_1985 | PFAM: helicase domain protein; DEAD/DEAH box helicase domain protein; SMART: DEAD-like helicases; KEGG: cph:Cpha266_1126 ATP-dependent DNA helicase RecQ. | KEGG: plt:Plut_1351 PAS/PAC sensor hybrid histidine kinase; TIGRFAM: PAS sensor protein; PFAM: response regulator receiver; ATP-binding region ATPase domain protein; histidine kinase A domain protein; PAS fold-3 domain protein; PAS fold-4 domain protein; PAS fold domain protein; SMART: PAS domain containing protein; PAC repeat-containing protein. | 0.455 |
| Ppha_1436 | Ppha_2807 | Ppha_1436 | Ppha_2807 | PFAM: helicase domain protein; DEAD/DEAH box helicase domain protein; SMART: DEAD-like helicases; KEGG: cph:Cpha266_1126 ATP-dependent DNA helicase RecQ. | PFAM: Prephenate dehydrogenase; KEGG: cph:Cpha266_2572 prephenate dehydrogenase. | 0.530 |
| Ppha_1436 | apt | Ppha_1436 | Ppha_0460 | PFAM: helicase domain protein; DEAD/DEAH box helicase domain protein; SMART: DEAD-like helicases; KEGG: cph:Cpha266_1126 ATP-dependent DNA helicase RecQ. | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | 0.676 |
| Ppha_1436 | topA | Ppha_1436 | Ppha_2842 | PFAM: helicase domain protein; DEAD/DEAH box helicase domain protein; SMART: DEAD-like helicases; KEGG: cph:Cpha266_1126 ATP-dependent DNA helicase RecQ. | DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...] | 0.891 |
| Ppha_1436 | xerD | Ppha_1436 | Ppha_0927 | PFAM: helicase domain protein; DEAD/DEAH box helicase domain protein; SMART: DEAD-like helicases; KEGG: cph:Cpha266_1126 ATP-dependent DNA helicase RecQ. | Tyrosine recombinase XerD; Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC- XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids. | 0.533 |
| Ppha_1985 | Ppha_0928 | Ppha_1985 | Ppha_0928 | KEGG: plt:Plut_1351 PAS/PAC sensor hybrid histidine kinase; TIGRFAM: PAS sensor protein; PFAM: response regulator receiver; ATP-binding region ATPase domain protein; histidine kinase A domain protein; PAS fold-3 domain protein; PAS fold-4 domain protein; PAS fold domain protein; SMART: PAS domain containing protein; PAC repeat-containing protein. | Sun protein; Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA. | 0.529 |
| Ppha_1985 | Ppha_1436 | Ppha_1985 | Ppha_1436 | KEGG: plt:Plut_1351 PAS/PAC sensor hybrid histidine kinase; TIGRFAM: PAS sensor protein; PFAM: response regulator receiver; ATP-binding region ATPase domain protein; histidine kinase A domain protein; PAS fold-3 domain protein; PAS fold-4 domain protein; PAS fold domain protein; SMART: PAS domain containing protein; PAC repeat-containing protein. | PFAM: helicase domain protein; DEAD/DEAH box helicase domain protein; SMART: DEAD-like helicases; KEGG: cph:Cpha266_1126 ATP-dependent DNA helicase RecQ. | 0.455 |
| Ppha_1985 | xerD | Ppha_1985 | Ppha_0927 | KEGG: plt:Plut_1351 PAS/PAC sensor hybrid histidine kinase; TIGRFAM: PAS sensor protein; PFAM: response regulator receiver; ATP-binding region ATPase domain protein; histidine kinase A domain protein; PAS fold-3 domain protein; PAS fold-4 domain protein; PAS fold domain protein; SMART: PAS domain containing protein; PAC repeat-containing protein. | Tyrosine recombinase XerD; Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC- XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids. | 0.508 |
| Ppha_2359 | Ppha_2438 | Ppha_2359 | Ppha_2438 | PFAM: cell divisionFtsK/SpoIIIE; SMART: AAA ATPase; KEGG: cph:Cpha266_2016 cell divisionFtsK/SpoIIIE. | TIGRFAM: parB-like partition protein; PFAM: ParB domain protein nuclease; KEGG: cph:Cpha266_2096 chromosome segregation DNA-binding protein; Belongs to the ParB family. | 0.807 |
| Ppha_2359 | mfd | Ppha_2359 | Ppha_2147 | PFAM: cell divisionFtsK/SpoIIIE; SMART: AAA ATPase; KEGG: cph:Cpha266_2016 cell divisionFtsK/SpoIIIE. | Transcription-repair coupling factor; Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site; In the C-terminal section; belongs to the helicase family. RecG subfamily. | 0.555 |
| Ppha_2359 | topA | Ppha_2359 | Ppha_2842 | PFAM: cell divisionFtsK/SpoIIIE; SMART: AAA ATPase; KEGG: cph:Cpha266_2016 cell divisionFtsK/SpoIIIE. | DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...] | 0.611 |
| Ppha_2359 | xerD | Ppha_2359 | Ppha_0927 | PFAM: cell divisionFtsK/SpoIIIE; SMART: AAA ATPase; KEGG: cph:Cpha266_2016 cell divisionFtsK/SpoIIIE. | Tyrosine recombinase XerD; Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC- XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids. | 0.670 |
| Ppha_2438 | Ppha_2359 | Ppha_2438 | Ppha_2359 | TIGRFAM: parB-like partition protein; PFAM: ParB domain protein nuclease; KEGG: cph:Cpha266_2096 chromosome segregation DNA-binding protein; Belongs to the ParB family. | PFAM: cell divisionFtsK/SpoIIIE; SMART: AAA ATPase; KEGG: cph:Cpha266_2016 cell divisionFtsK/SpoIIIE. | 0.807 |
| Ppha_2438 | mfd | Ppha_2438 | Ppha_2147 | TIGRFAM: parB-like partition protein; PFAM: ParB domain protein nuclease; KEGG: cph:Cpha266_2096 chromosome segregation DNA-binding protein; Belongs to the ParB family. | Transcription-repair coupling factor; Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site; In the C-terminal section; belongs to the helicase family. RecG subfamily. | 0.460 |
| Ppha_2438 | topA | Ppha_2438 | Ppha_2842 | TIGRFAM: parB-like partition protein; PFAM: ParB domain protein nuclease; KEGG: cph:Cpha266_2096 chromosome segregation DNA-binding protein; Belongs to the ParB family. | DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...] | 0.489 |
| Ppha_2438 | xerD | Ppha_2438 | Ppha_0927 | TIGRFAM: parB-like partition protein; PFAM: ParB domain protein nuclease; KEGG: cph:Cpha266_2096 chromosome segregation DNA-binding protein; Belongs to the ParB family. | Tyrosine recombinase XerD; Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC- XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids. | 0.519 |