Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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experimentally determined
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gene co-occurrence
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[Homology]
Score
menA1,4-dihydroxy-2-naphthoate octaprenyltransferase; Conversion of 1,4-dihydroxy-2-naphthoate (DHNA) to demethylmenaquinone (DMK); Belongs to the MenA family. Type 1 subfamily. (304 aa)    
Predicted Functional Partners:
Ppha_1616
PFAM: thioesterase superfamily protein; KEGG: cch:Cag_0930 phenylacetic acid degradation-related protein.
 
  
 0.928
menG
Ubiquinone/menaquinone biosynthesis methyltransferase; Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2).
 
  
 0.920
Ppha_1534
PFAM: Polyprenyl synthetase; KEGG: cch:Cag_0963 polyprenyl synthetase; Belongs to the FPP/GGPP synthase family.
    
 0.833
menD
2-succinyl-6-hydroxy-2, 4-cyclohexadiene-1-carboxylic acid synthase/2-oxoglutarate decarboxylase; Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2- succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC).
 
   
 0.826
menB
Naphthoate synthase; Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4-dihydroxy-2- naphthoyl-CoA (DHNA-CoA).
 
   
 0.816
Ppha_0029
TIGRFAM: geranylgeranyl reductase; PFAM: monooxygenase FAD-binding; FAD dependent oxidoreductase; KEGG: cch:Cag_0035 geranylgeranyl reductase.
  
 
 0.809
Ppha_1024
PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; HI0933 family protein; KEGG: cph:Cpha266_1905 FAD-dependent pyridine nucleotide-disulphide oxidoreductase.
  
    0.809
Ppha_1026
PFAM: Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase; KEGG: cph:Cpha266_1903 nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase.
       0.741
Ppha_1023
KEGG: cph:Cpha266_1906 hypothetical protein.
       0.722
menF
Isochorismate synthase; Catalyzes the conversion of chorismate to isochorismate.
 
   
 0.674
Your Current Organism:
Pelodictyon phaeoclathratiforme
NCBI taxonomy Id: 324925
Other names: P. phaeoclathratiforme BU-1, Pelodictyon phaeoclathratiforme BU-1, Pelodictyon phaeoclathratiforme DSM 5477, Pelodictyon phaeoclathratiforme str. BU-1, Pelodictyon phaeoclathratiforme strain BU-1
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