STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Ppha_1027PFAM: peptidase M48 Ste24p; KEGG: cph:Cpha266_1902 STE24 endopeptidase. (418 aa)    
Predicted Functional Partners:
Ppha_1028
Agmatine deiminase; PFAM: Porphyromonas-type peptidyl-arginine deiminase; KEGG: cph:Cpha266_1901 porphyromonas-type peptidyl-arginine deiminase; Belongs to the agmatine deiminase family.
       0.740
Ppha_1026
PFAM: Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase; KEGG: cph:Cpha266_1903 nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase.
       0.618
Ppha_1024
PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; HI0933 family protein; KEGG: cph:Cpha266_1905 FAD-dependent pyridine nucleotide-disulphide oxidoreductase.
  
    0.617
menA
1,4-dihydroxy-2-naphthoate octaprenyltransferase; Conversion of 1,4-dihydroxy-2-naphthoate (DHNA) to demethylmenaquinone (DMK); Belongs to the MenA family. Type 1 subfamily.
  
    0.613
Ppha_1023
KEGG: cph:Cpha266_1906 hypothetical protein.
       0.544
Ppha_1652
FAD linked oxidase domain protein; PFAM: protein of unknown function DUF224 cysteine-rich region domain protein; FAD linked oxidase domain protein; KEGG: cch:Cag_0799 oxidoreductase, FAD-binding.
 
   
 0.496
Ppha_1022
Hypothetical protein.
       0.492
msrA
Peptide methionine sulfoxide reductase; Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.
  
  
 0.455
grpE
GrpE protein; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent i [...]
  
  
 0.434
Ppha_0249
KEGG: cph:Cpha266_2448 hypothetical protein.
  
     0.401
Your Current Organism:
Pelodictyon phaeoclathratiforme
NCBI taxonomy Id: 324925
Other names: P. phaeoclathratiforme BU-1, Pelodictyon phaeoclathratiforme BU-1, Pelodictyon phaeoclathratiforme DSM 5477, Pelodictyon phaeoclathratiforme str. BU-1, Pelodictyon phaeoclathratiforme strain BU-1
Server load: low (26%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.