STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Ppha_1089Malate dehydrogenase (oxaloacetate-decarboxylating); PFAM: malic protein domain protein; malic protein NAD-binding; KEGG: cph:Cpha266_1271 malate dehydrogenase (oxaloacetate-decarboxylating). (409 aa)    
Predicted Functional Partners:
Ppha_0695
PFAM: 4Fe-4S ferredoxin iron-sulfur binding domain protein; pyruvate ferredoxin/flavodoxin oxidoreductase; pyruvate flavodoxin/ferredoxin oxidoreductase domain protein; KEGG: cph:Cpha266_0571 pyruvate flavodoxin/ferredoxin oxidoreductase domain protein.
  
 
 0.960
Ppha_1569
Hydro-lyase, Fe-S type, tartrate/fumarate subfamily, alpha subunit; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family.
  
 
 0.956
mdh
Malate dehydrogenase, NAD-dependent; Catalyzes the reversible oxidation of malate to oxaloacetate. Belongs to the LDH/MDH superfamily. MDH type 3 family.
  
 0.949
Ppha_1568
Oxaloacetate decarboxylase; PFAM: biotin/lipoyl attachment domain-containing protein; pyruvate carboxyltransferase; KEGG: cch:Cag_0859 oxaloacetate decarboxylase, alpha subunit.
    
 0.940
Ppha_2670
PFAM: pyruvate flavodoxin/ferredoxin oxidoreductase domain protein; KEGG: cph:Cpha266_0241 pyruvate flavodoxin/ferredoxin oxidoreductase domain protein.
  
 
 0.937
Ppha_0629
KEGG: cph:Cpha266_0518 pyruvate phosphate dikinase; TIGRFAM: pyruvate, phosphate dikinase; PFAM: PEP-utilizing protein; pyruvate phosphate dikinase PEP/pyruvate-binding; PEP-utilising protein mobile region; Belongs to the PEP-utilizing enzyme family.
  
 
 0.929
Ppha_0863
D-lactate dehydrogenase (cytochrome); PFAM: FAD linked oxidase domain protein; KEGG: pvi:Cvib_1206 D-lactate dehydrogenase (cytochrome).
  
 
 0.914
Ppha_0944
KEGG: plt:Plut_1434 Na+-transporting methylmalonyl-CoA/oxaloacetate decarboxylase, beta subunit; TIGRFAM: sodium ion-translocating decarboxylase, beta subunit; PFAM: Na+transporting methylmalonyl-CoA/oxaloacetate decarboxylase beta subunit.
    
 0.914
Ppha_2671
PFAM: thiamine pyrophosphate protein domain protein TPP-binding; KEGG: cph:Cpha266_0240 2-oxoglutarate ferredoxin oxidoreductase subunit beta.
     
 0.911
Ppha_2168
TIGRFAM: acetolactate synthase, large subunit, biosynthetic type; PFAM: thiamine pyrophosphate protein domain protein TPP-binding; thiamine pyrophosphate protein central region; thiamine pyrophosphate protein TPP binding domain protein; KEGG: cph:Cpha266_0853 acetolactate synthase, large subunit.
  
 
 0.865
Your Current Organism:
Pelodictyon phaeoclathratiforme
NCBI taxonomy Id: 324925
Other names: P. phaeoclathratiforme BU-1, Pelodictyon phaeoclathratiforme BU-1, Pelodictyon phaeoclathratiforme DSM 5477, Pelodictyon phaeoclathratiforme str. BU-1, Pelodictyon phaeoclathratiforme strain BU-1
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.