Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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from curated databases
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Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Ppha_1093PFAM: DegT/DnrJ/EryC1/StrS aminotransferase; KEGG: cch:Cag_0448 DegT/DnrJ/EryC1/StrS family protein; Belongs to the DegT/DnrJ/EryC1 family. (436 aa)    
Predicted Functional Partners:
Ppha_1214
PFAM: oxidoreductase domain protein; Oxidoreductase domain; KEGG: cch:Cag_0723 oxidoreductase, Gfo/Idh/MocA family.
 
  
 0.705
Ppha_0520
Polysaccharide biosynthesis protein CapD; PFAM: NAD-dependent epimerase/dehydratase; short-chain dehydrogenase/reductase SDR; 3-beta hydroxysteroid dehydrogenase/isomerase; polysaccharide biosynthesis protein CapD; dTDP-4-dehydrorhamnose reductase; Male sterility domain; KEGG: cph:Cpha266_2635 polysaccharide biosynthesis protein CapD.
 
  
 0.680
htpG
Heat shock protein Hsp90; Molecular chaperone. Has ATPase activity.
   
  
 0.634
miaB
RNA modification enzyme, MiaB family; Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6- (dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine.
   
  
 0.626
Ppha_2495
PFAM: peptidase U32; KEGG: cph:Cpha266_2165 peptidase U32.
      
 0.623
prfC
Peptide chain release factor 3; Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF-1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP. Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. PrfC subfamily.
      
 0.618
Ppha_1092
TIGRFAM: UDP-N-acetylmuramate; PFAM: cytoplasmic peptidoglycan synthetase domain protein; Mur ligase middle domain protein; KEGG: cph:Cpha266_1869 UDP-N-acetylmuramate--L-alanine ligase.
       0.560
Ppha_0533
PFAM: oxidoreductase domain protein; KEGG: pmf:P9303_01161 hypothetical protein.
 
  
 0.544
gyrA
DNA gyrase, A subunit; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
      
 0.524
Ppha_0558
Polysaccharide biosynthesis protein CapD; PFAM: NAD-dependent epimerase/dehydratase; 3-beta hydroxysteroid dehydrogenase/isomerase; polysaccharide biosynthesis protein CapD; dTDP-4-dehydrorhamnose reductase; Male sterility domain; Polysaccharide biosynthesis domain protein; KEGG: gur:Gura_1672 polysaccharide biosynthesis protein CapD.
  
  
 0.517
Your Current Organism:
Pelodictyon phaeoclathratiforme
NCBI taxonomy Id: 324925
Other names: P. phaeoclathratiforme BU-1, Pelodictyon phaeoclathratiforme BU-1, Pelodictyon phaeoclathratiforme DSM 5477, Pelodictyon phaeoclathratiforme str. BU-1, Pelodictyon phaeoclathratiforme strain BU-1
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