Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
Ppha_1095PFAM: alpha/beta hydrolase fold; KEGG: cph:Cpha266_2528 alpha/beta hydrolase fold. (302 aa)    
Predicted Functional Partners:
Ppha_1094
PFAM: major facilitator superfamily MFS_1; KEGG: cch:Cag_0889 transporter, putative.
 
     0.859
Ppha_0829
PFAM: alpha/beta hydrolase fold; KEGG: cch:Cag_1299 dihydrolipoamide acetyltransferase, putative.
  
     0.697
Ppha_1096
KEGG: cph:Cpha266_0092 virulence associated protein B.
       0.675
Ppha_2549
PFAM: alpha/beta hydrolase fold; KEGG: cch:Cag_1627 3-oxoadipate enol-lactonase, putative.
  
     0.636
Ppha_1097
KEGG: mar:MAE_20900 hypothetical protein.
       0.624
Ppha_1098
KEGG: mar:MAE_20890 hypothetical protein.
       0.624
Ppha_2097
PFAM: alpha/beta hydrolase fold; KEGG: cph:Cpha266_0919 alpha/beta hydrolase fold.
  
     0.591
proA
Gamma-glutamyl phosphate reductase; Catalyzes the NADPH-dependent reduction of L-glutamate 5- phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate. Belongs to the gamma-glutamyl phosphate reductase family.
     
 0.576
lolD-2
ABC transporter related; Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner.
  
    0.571
proB
Glutamate 5-kinase; Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate.
     
 0.566
Your Current Organism:
Pelodictyon phaeoclathratiforme
NCBI taxonomy Id: 324925
Other names: P. phaeoclathratiforme BU-1, Pelodictyon phaeoclathratiforme BU-1, Pelodictyon phaeoclathratiforme DSM 5477, Pelodictyon phaeoclathratiforme str. BU-1, Pelodictyon phaeoclathratiforme strain BU-1
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