STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Ppha_1114KEGG: cph:Cpha266_1071 hypothetical protein. (295 aa)    
Predicted Functional Partners:
Ppha_1115
methylated-DNA/protein-cysteine methyltransferase; Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated.
       0.773
Ppha_2309
PFAM: Polysulphide reductase NrfD; KEGG: cph:Cpha266_0140 polysulphide reductase, NrfD.
  
     0.582
Ppha_2314
KEGG: cch:Cag_1949 hypothetical protein.
  
     0.578
Ppha_2311
KEGG: cch:Cag_1946 hypothetical protein.
  
     0.527
Ppha_1116
Transcriptional regulator, AraC family; PFAM: helix-turn-helix- domain containing protein AraC type; KEGG: plt:Plut_0805 transcriptional regulator, AraC family.
       0.476
Ppha_0686
PFAM: Methyltransferase type 11; Methyltransferase type 12; KEGG: cph:Cpha266_0562 methyltransferase type 12.
  
     0.466
Ppha_2313
PFAM: Nitrate reductase gamma subunit; KEGG: cph:Cpha266_0136 nitrate reductase, gamma subunit.
  
     0.455
Ppha_0035
KEGG: cch:Cag_1582 heterodisulfide reductase, putative.
  
     0.431
Ppha_1117
TIGRFAM: efflux transporter, RND family, MFP subunit; PFAM: biotin/lipoyl attachment domain-containing protein; secretion protein HlyD family protein; KEGG: cph:Cpha266_1564 efflux transporter, RND family, MFP subunit; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.
       0.425
Your Current Organism:
Pelodictyon phaeoclathratiforme
NCBI taxonomy Id: 324925
Other names: P. phaeoclathratiforme BU-1, Pelodictyon phaeoclathratiforme BU-1, Pelodictyon phaeoclathratiforme DSM 5477, Pelodictyon phaeoclathratiforme str. BU-1, Pelodictyon phaeoclathratiforme strain BU-1
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