STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Ppha_1126PFAM: helicase domain protein; SMART: DEAD-like helicases; KEGG: cte:CT0906 DNA-dependent ATPase, SNF2 family protein. (1064 aa)    
Predicted Functional Partners:
Ppha_1127
KEGG: cte:CT0907 hypothetical protein.
 
     0.955
Ppha_1130
KEGG: cte:CT0911 type III restriction system endonuclease.
 
     0.954
Ppha_1128
Site-specific DNA-methyltransferase (adenine-specific); PFAM: DNA methylase N-4/N-6 domain protein; KEGG: bpt:Bpet4236 type III restriction system methylase.
 
     0.953
Ppha_1129
PFAM: protein of unknown function DUF1016; KEGG: amr:AM1_2231 hypothetical protein.
       0.790
Ppha_2240
PFAM: DNA methylase N-4/N-6 domain protein; KEGG: gur:Gura_4390 site-specific DNA-methyltransferase (adenine-specific).
 
     0.776
Ppha_1980
PFAM: DNA methylase N-4/N-6 domain protein; KEGG: btr:Btr_1180 methyltransferase.
 
     0.659
polA
DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family.
  
 0.621
Ppha_0002
DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...]
   
 0.549
rpoA
DNA-directed RNA polymerase, alpha subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
   
 0.545
rpoB
DNA-directed RNA polymerase, beta subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
    
 0.542
Your Current Organism:
Pelodictyon phaeoclathratiforme
NCBI taxonomy Id: 324925
Other names: P. phaeoclathratiforme BU-1, Pelodictyon phaeoclathratiforme BU-1, Pelodictyon phaeoclathratiforme DSM 5477, Pelodictyon phaeoclathratiforme str. BU-1, Pelodictyon phaeoclathratiforme strain BU-1
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