Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
Ppha_1148Serine-type D-Ala-D-Ala carboxypeptidase; PFAM: peptidase S11 D-alanyl-D-alanine carboxypeptidase 1; KEGG: cch:Cag_1081 D-alanyl-D-alanine carboxypeptidase; Belongs to the peptidase S11 family. (390 aa)    
Predicted Functional Partners:
Ppha_2899
Peptidoglycan glycosyltransferase; PFAM: penicillin-binding protein transpeptidase; Penicillin-binding protein dimerisation domain; PASTA domain containing protein; KEGG: cph:Cpha266_2727 peptidoglycan glycosyltransferase.
 
 
 0.947
mtgA
Monofunctional biosynthetic peptidoglycan transglycosylase; Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors; Belongs to the glycosyltransferase 51 family.
 
 
 0.935
Ppha_0864
Penicillin-binding protein 2; KEGG: cph:Cpha266_0817 peptidoglycan glycosyltransferase; TIGRFAM: penicillin-binding protein 2; PFAM: penicillin-binding protein transpeptidase; Penicillin-binding protein dimerisation domain.
  
 
 0.928
Ppha_2643
TIGRFAM: penicillin-binding protein, 1A family; PFAM: glycosyl transferase family 51; penicillin-binding protein transpeptidase; KEGG: cch:Cag_0590 penicillin-binding protein 1A.
     
 0.924
Ppha_1149
PFAM: Stress responsive alpha-beta barrel domain protein; KEGG: cte:CT1263 hypothetical protein.
       0.774
murF
UDP-N-acetylmuramyl-tripeptide synthetase; Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan. Belongs to the MurCDEF family. MurE subfamily.
 
  
 0.612
Ppha_1147
PFAM: Lysine exporter protein (LYSE/YGGA); KEGG: cte:CT1267 amino acid efflux protein, putative.
       0.541
Ppha_2895
PFAM: cell cycle protein; KEGG: cph:Cpha266_2722 cell cycle protein; Belongs to the SEDS family.
 
  
 0.504
ddl
D-alanine/D-alanine ligase; Cell wall formation.
 
  
 0.460
Ppha_1146
KEGG: cph:Cpha266_1423 hypothetical protein.
       0.426
Your Current Organism:
Pelodictyon phaeoclathratiforme
NCBI taxonomy Id: 324925
Other names: P. phaeoclathratiforme BU-1, Pelodictyon phaeoclathratiforme BU-1, Pelodictyon phaeoclathratiforme DSM 5477, Pelodictyon phaeoclathratiforme str. BU-1, Pelodictyon phaeoclathratiforme strain BU-1
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