| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| Ppha_1151 | Ppha_1152 | Ppha_1151 | Ppha_1152 | PFAM: 4Fe-4S ferredoxin iron-sulfur binding domain protein; KEGG: plt:Plut_1215 ferredoxin, 4Fe-4S. | PFAM: PhoH family protein; KEGG: cch:Cag_1083 PhoH family protein. | 0.494 |
| Ppha_1151 | hldD | Ppha_1151 | Ppha_1153 | PFAM: 4Fe-4S ferredoxin iron-sulfur binding domain protein; KEGG: plt:Plut_1215 ferredoxin, 4Fe-4S. | ADP-L-glycero-D-manno-heptose-6-epimerase; Catalyzes the interconversion between ADP-D-glycero-beta-D- manno-heptose and ADP-L-glycero-beta-D-manno-heptose via an epimerization at carbon 6 of the heptose; Belongs to the NAD(P)-dependent epimerase/dehydratase family. HldD subfamily. | 0.484 |
| Ppha_1152 | Ppha_1151 | Ppha_1152 | Ppha_1151 | PFAM: PhoH family protein; KEGG: cch:Cag_1083 PhoH family protein. | PFAM: 4Fe-4S ferredoxin iron-sulfur binding domain protein; KEGG: plt:Plut_1215 ferredoxin, 4Fe-4S. | 0.494 |
| Ppha_1152 | Ppha_1154 | Ppha_1152 | Ppha_1154 | PFAM: PhoH family protein; KEGG: cch:Cag_1083 PhoH family protein. | KEGG: cph:Cpha266_1549 PAS/PAC sensor hybrid histidine kinase; TIGRFAM: PAS sensor protein; PFAM: response regulator receiver; ATP-binding region ATPase domain protein; histidine kinase A domain protein; PAS fold-3 domain protein; PAS fold-4 domain protein; PAS fold domain protein; SMART: PAS domain containing protein; PAC repeat-containing protein. | 0.540 |
| Ppha_1152 | coaD | Ppha_1152 | Ppha_1192 | PFAM: PhoH family protein; KEGG: cch:Cag_1083 PhoH family protein. | Pantetheine-phosphate adenylyltransferase; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the bacterial CoaD family. | 0.421 |
| Ppha_1152 | era | Ppha_1152 | Ppha_0456 | PFAM: PhoH family protein; KEGG: cch:Cag_1083 PhoH family protein. | GTP-binding protein Era; An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism. | 0.442 |
| Ppha_1152 | hisC | Ppha_1152 | Ppha_1156 | PFAM: PhoH family protein; KEGG: cch:Cag_1083 PhoH family protein. | TIGRFAM: histidinol-phosphate aminotransferase; PFAM: aminotransferase class I and II; KEGG: pvi:Cvib_0754 histidinol phosphate aminotransferase; Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily. | 0.422 |
| Ppha_1152 | hldD | Ppha_1152 | Ppha_1153 | PFAM: PhoH family protein; KEGG: cch:Cag_1083 PhoH family protein. | ADP-L-glycero-D-manno-heptose-6-epimerase; Catalyzes the interconversion between ADP-D-glycero-beta-D- manno-heptose and ADP-L-glycero-beta-D-manno-heptose via an epimerization at carbon 6 of the heptose; Belongs to the NAD(P)-dependent epimerase/dehydratase family. HldD subfamily. | 0.766 |
| Ppha_1152 | recO | Ppha_1152 | Ppha_2799 | PFAM: PhoH family protein; KEGG: cch:Cag_1083 PhoH family protein. | DNA repair protein RecO; Involved in DNA repair and RecF pathway recombination. | 0.721 |
| Ppha_1152 | rsfS | Ppha_1152 | Ppha_0095 | PFAM: PhoH family protein; KEGG: cch:Cag_1083 PhoH family protein. | Iojap-like protein; Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation. | 0.453 |
| Ppha_1152 | tadA | Ppha_1152 | Ppha_0777 | PFAM: PhoH family protein; KEGG: cch:Cag_1083 PhoH family protein. | CMP/dCMP deaminase zinc-binding; Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2); Belongs to the cytidine and deoxycytidylate deaminase family. | 0.580 |
| Ppha_1152 | ybeY | Ppha_1152 | Ppha_1730 | PFAM: PhoH family protein; KEGG: cch:Cag_1083 PhoH family protein. | Protein of unknown function UPF0054; Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA. | 0.910 |
| Ppha_1154 | Ppha_1152 | Ppha_1154 | Ppha_1152 | KEGG: cph:Cpha266_1549 PAS/PAC sensor hybrid histidine kinase; TIGRFAM: PAS sensor protein; PFAM: response regulator receiver; ATP-binding region ATPase domain protein; histidine kinase A domain protein; PAS fold-3 domain protein; PAS fold-4 domain protein; PAS fold domain protein; SMART: PAS domain containing protein; PAC repeat-containing protein. | PFAM: PhoH family protein; KEGG: cch:Cag_1083 PhoH family protein. | 0.540 |
| Ppha_1154 | hldD | Ppha_1154 | Ppha_1153 | KEGG: cph:Cpha266_1549 PAS/PAC sensor hybrid histidine kinase; TIGRFAM: PAS sensor protein; PFAM: response regulator receiver; ATP-binding region ATPase domain protein; histidine kinase A domain protein; PAS fold-3 domain protein; PAS fold-4 domain protein; PAS fold domain protein; SMART: PAS domain containing protein; PAC repeat-containing protein. | ADP-L-glycero-D-manno-heptose-6-epimerase; Catalyzes the interconversion between ADP-D-glycero-beta-D- manno-heptose and ADP-L-glycero-beta-D-manno-heptose via an epimerization at carbon 6 of the heptose; Belongs to the NAD(P)-dependent epimerase/dehydratase family. HldD subfamily. | 0.558 |
| coaD | Ppha_1152 | Ppha_1192 | Ppha_1152 | Pantetheine-phosphate adenylyltransferase; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the bacterial CoaD family. | PFAM: PhoH family protein; KEGG: cch:Cag_1083 PhoH family protein. | 0.421 |
| coaD | rsfS | Ppha_1192 | Ppha_0095 | Pantetheine-phosphate adenylyltransferase; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the bacterial CoaD family. | Iojap-like protein; Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation. | 0.434 |
| era | Ppha_1152 | Ppha_0456 | Ppha_1152 | GTP-binding protein Era; An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism. | PFAM: PhoH family protein; KEGG: cch:Cag_1083 PhoH family protein. | 0.442 |
| era | recO | Ppha_0456 | Ppha_2799 | GTP-binding protein Era; An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism. | DNA repair protein RecO; Involved in DNA repair and RecF pathway recombination. | 0.624 |
| era | ybeY | Ppha_0456 | Ppha_1730 | GTP-binding protein Era; An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism. | Protein of unknown function UPF0054; Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA. | 0.722 |
| hisC | Ppha_1152 | Ppha_1156 | Ppha_1152 | TIGRFAM: histidinol-phosphate aminotransferase; PFAM: aminotransferase class I and II; KEGG: pvi:Cvib_0754 histidinol phosphate aminotransferase; Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily. | PFAM: PhoH family protein; KEGG: cch:Cag_1083 PhoH family protein. | 0.422 |