Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
Ppha_1217PFAM: type III restriction protein res subunit; protein of unknown function DUF450; SMART: DEAD-like helicases; KEGG: spc:Sputcn32_3523 protein of unknown function DUF450. (1042 aa)    
Predicted Functional Partners:
Ppha_1218
PFAM: N-6 DNA methylase; KEGG: spc:Sputcn32_3524 N-6 DNA methylase.
 
  
 0.965
Ppha_1219
KEGG: spc:Sputcn32_3525 restriction modification system DNA specificity domain.
 
  
 0.964
Ppha_0745
PFAM: restriction modification system DNA specificity domain; KEGG: vei:Veis_3549 restriction modification system DNA specificity domain.
 
  
 0.718
Ppha_0750
TIGRFAM: type I restriction-modification system, M subunit; PFAM: N-6 DNA methylase; KEGG: vei:Veis_3546 type I restriction-modification system, M subunit.
 
  
 0.669
Ppha_2394
KEGG: xom:XOO_3260 hypothetical protein.
 
  
 0.581
Ppha_0913
KEGG: cph:Cpha266_1712 N-6 DNA methylase.
 
  
 0.548
Ppha_1452
PFAM: restriction modification system DNA specificity domain; KEGG: cch:Cag_1526 restriction endonuclease S subunits-like.
 
  
 0.534
Ppha_1454
PFAM: putative RNA methylase; N-6 DNA methylase; KEGG: cph:Cpha266_1130 N-6 DNA methylase.
 
  
 0.506
Ppha_1216
PFAM: periplasmic binding protein; KEGG: plt:Plut_1148 ABC transporter, periplasmic substrate-binding protein.
       0.496
Ppha_1604
KEGG: mma:MM_2294 type I restriction-modification system specificity subunit.
 
  
 0.465
Your Current Organism:
Pelodictyon phaeoclathratiforme
NCBI taxonomy Id: 324925
Other names: P. phaeoclathratiforme BU-1, Pelodictyon phaeoclathratiforme BU-1, Pelodictyon phaeoclathratiforme DSM 5477, Pelodictyon phaeoclathratiforme str. BU-1, Pelodictyon phaeoclathratiforme strain BU-1
Server load: low (24%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.