STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Ppha_1233PFAM: AAA ATPase central domain protein; SMART: AAA ATPase; KEGG: cph:Cpha266_2260 AAA ATPase, central domain protein. (510 aa)    
Predicted Functional Partners:
Ppha_1232
KEGG: cph:Cpha266_2261 DnaK like protein; Belongs to the heat shock protein 70 family.
 
 0.926
Ppha_1234
PFAM: protein of unknown function DUF323; KEGG: cph:Cpha266_2259 protein of unknown function DUF323.
 
     0.744
htpG
Heat shock protein Hsp90; Molecular chaperone. Has ATPase activity.
   
 0.651
Ppha_0002
DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...]
  
 
 0.639
Ppha_2627
Glycerol kinase; Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate.
   
  0.636
Ppha_1231
KEGG: cph:Cpha266_2262 hypothetical protein.
       0.626
Ppha_1369
DNA-directed DNA polymerase; PFAM: UMUC domain protein DNA-repair protein; KEGG: cph:Cpha266_1031 DNA-directed DNA polymerase.
     
 0.547
Ppha_2917
SEFIR domain protein; PFAM: TPR repeat-containing protein; Tetratricopeptide TPR_2 repeat protein; SEFIR domain protein; SMART: Tetratricopeptide domain protein; KEGG: nwi:Nwi_3004 TPR repeat protein.
 
 
 0.474
Ppha_0634
PFAM: PpiC-type peptidyl-prolyl cis-trans isomerase; KEGG: cph:Cpha266_1844 hypothetical protein.
  
     0.465
Ppha_0637
PFAM: TPR repeat-containing protein; Tetratricopeptide TPR_3; Tetratricopeptide TPR_4; Tetratricopeptide TPR_2 repeat protein; SMART: Tetratricopeptide domain protein; KEGG: cph:Cpha266_1841 TPR repeat-containing protein.
 
 0.455
Your Current Organism:
Pelodictyon phaeoclathratiforme
NCBI taxonomy Id: 324925
Other names: P. phaeoclathratiforme BU-1, Pelodictyon phaeoclathratiforme BU-1, Pelodictyon phaeoclathratiforme DSM 5477, Pelodictyon phaeoclathratiforme str. BU-1, Pelodictyon phaeoclathratiforme strain BU-1
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