Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
Ppha_1270PFAM: Xylose isomerase domain protein TIM barrel; KEGG: cch:Cag_1076 hypothetical protein. (268 aa)    
Predicted Functional Partners:
Ppha_1267
TIGRFAM: cob(I)alamin adenosyltransferase; PFAM: ATP:corrinoid adenosyltransferase BtuR/CobO/CobP; KEGG: cph:Cpha266_1120 cob(I)yrinic acid a,c-diamide adenosyltransferase.
    
  0.977
cobD
Cobalamin biosynthesis protein CobD; Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group.
    
  0.971
Ppha_1293
Adenosylcobinamide-phosphate guanylyltransferase; PFAM: cobalbumin biosynthesis protein; KEGG: cch:Cag_0846 cobalamin biosynthesis protein CobP.
 
  
  0.922
cobS
Cobalamin 5'-phosphate synthase; Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'- phosphate; Belongs to the CobS family.
    
  0.907
Ppha_1268
PFAM: transport system permease protein; KEGG: cch:Cag_0754 FecCD transport family protein; Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
       0.781
Ppha_1269
PFAM: SMC domain protein; ABC transporter related; SMART: AAA ATPase; KEGG: cch:Cag_1079 ATPase.
       0.781
cobQ
Cobyric acid synthase CobQ; Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation. Belongs to the CobB/CobQ family. CobQ subfamily.
       0.727
Ppha_2162
KEGG: cph:Cpha266_0858 transcriptional regulator, Fis family.
  
     0.726
Ppha_1265
TIGRFAM: L-threonine-O-3-phosphate decarboxylase; PFAM: aminotransferase class I and II; KEGG: cch:Cag_1011 L-threonine-O-3-phosphate decarboxylase.
       0.715
Ppha_1263
TIGRFAM: cob(II)yrinic acid a,c-diamide reductase; PFAM: nitroreductase; KEGG: cph:Cpha266_1116 cob(II)yrinic acid a,c-diamide reductase.
       0.709
Your Current Organism:
Pelodictyon phaeoclathratiforme
NCBI taxonomy Id: 324925
Other names: P. phaeoclathratiforme BU-1, Pelodictyon phaeoclathratiforme BU-1, Pelodictyon phaeoclathratiforme DSM 5477, Pelodictyon phaeoclathratiforme str. BU-1, Pelodictyon phaeoclathratiforme strain BU-1
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