Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
Ppha_1319Two component, sigma54 specific, transcriptional regulator, Fis family; PFAM: response regulator receiver; sigma-54 factor interaction domain-containing protein; helix-turn-helix Fis-type; ATPase associated with various cellular activities AAA_5; SMART: AAA ATPase; KEGG: plt:Plut_0344 two component transcriptional regulator, fis family. (452 aa)    
Predicted Functional Partners:
Ppha_1318
Multi-sensor signal transduction histidine kinase; TIGRFAM: PAS sensor protein; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; PAS fold-4 domain protein; PAS fold domain protein; KEGG: plt:Plut_0343 multi-sensor signal transduction histidine kinase.
 
 
 0.841
Ppha_1207
TIGRFAM: RNA polymerase sigma-54 factor, RpoN; PFAM: sigma-54 factor; sigma-54 factor core-binding region; sigma-54 DNA-binding domain protein; KEGG: cch:Cag_0781 sigma-54 factor.
 
   
 0.777
Ppha_1799
KEGG: plt:Plut_1093 multi-sensor signal transduction histidine kinase; TIGRFAM: PAS sensor protein; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; PAS fold-3 domain protein; PAS fold-4 domain protein; PAS fold domain protein; SMART: PAS domain containing protein; PAC repeat-containing protein.
 
 
 
 0.557
Ppha_0229
KEGG: cch:Cag_0563 putative PAS/PAC sensor protein; TIGRFAM: PAS sensor protein; PFAM: CheB methylesterase; MCP methyltransferase CheR-type; PAS fold-4 domain protein; PAS fold domain protein; SMART: PAS domain containing protein.
  
 
 0.477
Ppha_1653
KEGG: cph:Cpha266_1788 putative PAS/PAC sensor protein; TIGRFAM: PAS sensor protein; PFAM: CheB methylesterase; MCP methyltransferase CheR-type; SMART: PAS domain containing protein.
  
 
 0.438
Ppha_1320
KEGG: pvi:Cvib_0916 hypothetical protein.
       0.420
Ppha_1427
KEGG: plt:Plut_1093 multi-sensor signal transduction histidine kinase; TIGRFAM: PAS sensor protein; PFAM: GAF domain protein; ATP-binding region ATPase domain protein; histidine kinase A domain protein; SMART: PAS domain containing protein.
 
 
 
 0.402
Your Current Organism:
Pelodictyon phaeoclathratiforme
NCBI taxonomy Id: 324925
Other names: P. phaeoclathratiforme BU-1, Pelodictyon phaeoclathratiforme BU-1, Pelodictyon phaeoclathratiforme DSM 5477, Pelodictyon phaeoclathratiforme str. BU-1, Pelodictyon phaeoclathratiforme strain BU-1
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