Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
Ppha_1422PFAM: SNF2-related protein; helicase domain protein; SMART: DEAD-like helicases; KEGG: cph:Cpha266_1301 helicase domain protein. (958 aa)    
Predicted Functional Partners:
Ppha_1423
PFAM: helicase domain protein; DEAD/DEAH box helicase domain protein; Helicase superfamily 1 and 2 ATP-binding; SMART: DEAD-like helicases; KEGG: cph:Cpha266_1302 DEAD/DEAH box helicase domain protein.
 
   
 0.967
rpoA
DNA-directed RNA polymerase, alpha subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
  
 0.966
rpoB
DNA-directed RNA polymerase, beta subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
  
 0.962
Ppha_1421
KEGG: dge:Dgeo_1545 putative type II DNA modification enzyme.
 
     0.949
rpoC
DNA-directed RNA polymerase, beta' subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
   
 0.925
Ppha_0373
PFAM: WD-40 repeat protein; KEGG: cch:Cag_0213 WD-40 repeat.
 
 0.905
Ppha_1253
PFAM: WD-40 repeat protein; KEGG: dar:Daro_3599 WD-40 repeat.
 
 0.899
rplC
Ribosomal protein L3; One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit; Belongs to the universal ribosomal protein uL3 family.
   
 
 0.897
Ppha_0273
SMART: TIR protein; KEGG: fal:FRAAL5311 hypothetical protein; putative transmembrane receptor activity.
  
 0.889
Ppha_1274
SMART: nuclear protein SET; KEGG: plt:Plut_1126 nuclear protein SET.
  
 0.889
Your Current Organism:
Pelodictyon phaeoclathratiforme
NCBI taxonomy Id: 324925
Other names: P. phaeoclathratiforme BU-1, Pelodictyon phaeoclathratiforme BU-1, Pelodictyon phaeoclathratiforme DSM 5477, Pelodictyon phaeoclathratiforme str. BU-1, Pelodictyon phaeoclathratiforme strain BU-1
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