Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
Ppha_1482PFAM: aminotransferase class V; Cys/Met metabolism pyridoxal-phosphate-dependent protein; DegT/DnrJ/EryC1/StrS aminotransferase; aromatic amino acid beta-eliminating lyase/threonine aldolase; KEGG: cch:Cag_1114 DegT/DnrJ/EryC1/StrS family protein; Belongs to the DegT/DnrJ/EryC1 family. (385 aa)    
Predicted Functional Partners:
Ppha_1483
PFAM: iron-containing alcohol dehydrogenase; KEGG: cch:Cag_1128 alcohol dehydrogenase, iron-containing.
       0.711
Ppha_1484
PFAM: acylneuraminate cytidylyltransferase; KEGG: cph:Cpha266_1514 acylneuraminate cytidylyltransferase.
  
  
 0.703
Ppha_0520
Polysaccharide biosynthesis protein CapD; PFAM: NAD-dependent epimerase/dehydratase; short-chain dehydrogenase/reductase SDR; 3-beta hydroxysteroid dehydrogenase/isomerase; polysaccharide biosynthesis protein CapD; dTDP-4-dehydrorhamnose reductase; Male sterility domain; KEGG: cph:Cpha266_2635 polysaccharide biosynthesis protein CapD.
 
  
 0.690
Ppha_1214
PFAM: oxidoreductase domain protein; Oxidoreductase domain; KEGG: cch:Cag_0723 oxidoreductase, Gfo/Idh/MocA family.
 
  
 0.676
miaB
RNA modification enzyme, MiaB family; Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6- (dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine.
   
  
 0.661
htpG
Heat shock protein Hsp90; Molecular chaperone. Has ATPase activity.
   
  
 0.657
prfC
Peptide chain release factor 3; Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF-1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP. Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. PrfC subfamily.
      
 0.655
Ppha_2495
PFAM: peptidase U32; KEGG: cph:Cpha266_2165 peptidase U32.
      
 0.655
Ppha_1485
KEGG: cph:Cpha266_1515 hypothetical protein.
  
    0.651
Ppha_1486
KEGG: cph:Cpha266_1516 hypothetical protein.
       0.638
Your Current Organism:
Pelodictyon phaeoclathratiforme
NCBI taxonomy Id: 324925
Other names: P. phaeoclathratiforme BU-1, Pelodictyon phaeoclathratiforme BU-1, Pelodictyon phaeoclathratiforme DSM 5477, Pelodictyon phaeoclathratiforme str. BU-1, Pelodictyon phaeoclathratiforme strain BU-1
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