Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
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[Homology]
Score
Ppha_1544TIGRFAM: thioredoxin reductase; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; KEGG: cch:Cag_1151 thioredoxin reductase. (311 aa)    
Predicted Functional Partners:
Ppha_1545
TIGRFAM: thioredoxin; PFAM: Thioredoxin domain; KEGG: pvi:Cvib_1012 thioredoxin; Belongs to the thioredoxin family.
 
 0.929
Ppha_1546
TIGRFAM: thioredoxin; PFAM: Redoxin domain protein; Thioredoxin domain; KEGG: pvi:Cvib_1012 thioredoxin; Belongs to the thioredoxin family.
 
 0.888
Ppha_1475
TIGRFAM: redox-active disulfide protein 2; KEGG: cch:Cag_0399 redox-active disulfide protein 2.
  
 
 0.665
Ppha_1854
TIGRFAM: thioredoxin; PFAM: Thioredoxin domain; KEGG: cph:Cpha266_1719 thioredoxin; Belongs to the thioredoxin family.
 
 
 0.646
Ppha_1082
PFAM: alkyl hydroperoxide reductase/ Thiol specific antioxidant/ Mal allergen; Redoxin domain protein; KEGG: cch:Cag_0700 thiolredoxin peroxidase.
  
 
 0.613
Ppha_1142
Alkyl hydroperoxide reductase/ Thiol specific antioxidant/ Mal allergen; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides.
  
 
 0.613
metG
methionyl-tRNA synthetase; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.
 
 
 0.540
Ppha_2005
PFAM: UBA/THIF-type NAD/FAD binding protein; MoeZ/MoeB domain protein; KEGG: cph:Cpha266_0728 UBA/ThiF-type NAD/FAD binding protein.
  
    0.502
msrA
Peptide methionine sulfoxide reductase; Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.
  
  
 0.486
Ppha_0452
PFAM: RNA binding S1 domain protein; KEGG: cch:Cag_0570 30S ribosomal protein S1.
 
    0.476
Your Current Organism:
Pelodictyon phaeoclathratiforme
NCBI taxonomy Id: 324925
Other names: P. phaeoclathratiforme BU-1, Pelodictyon phaeoclathratiforme BU-1, Pelodictyon phaeoclathratiforme DSM 5477, Pelodictyon phaeoclathratiforme str. BU-1, Pelodictyon phaeoclathratiforme strain BU-1
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