Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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from curated databases
textmining
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experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
Ppha_1546TIGRFAM: thioredoxin; PFAM: Redoxin domain protein; Thioredoxin domain; KEGG: pvi:Cvib_1012 thioredoxin; Belongs to the thioredoxin family. (114 aa)    
Predicted Functional Partners:
Ppha_1544
TIGRFAM: thioredoxin reductase; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; KEGG: cch:Cag_1151 thioredoxin reductase.
 
 0.888
groL
Chaperonin GroEL; Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions.
   
 
 0.690
Ppha_0876
Ribonucleoside-diphosphate reductase, adenosylcobalamin-dependent; Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and/or for immediate growth after restoration of oxygen.
  
 
 0.602
Ppha_1024
PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; HI0933 family protein; KEGG: cph:Cpha266_1905 FAD-dependent pyridine nucleotide-disulphide oxidoreductase.
  
 
 0.571
Ppha_1547
KEGG: cph:Cpha266_1195 DNA polymerase III, alpha subunit; TIGRFAM: DNA polymerase III, alpha subunit; PFAM: PHP domain protein; nucleic acid binding OB-fold tRNA/helicase-type; DNA polymerase III alpha subunit; SMART: phosphoesterase PHP domain protein.
  
  
 0.565
Ppha_0781
PFAM: glutamine amidotransferase class-II; glutamate synthase alpha subunit domain protein; ferredoxin-dependent glutamate synthase; glutamate synthase; KEGG: plt:Plut_0502 glutamate synthase (ferredoxin).
   
 
 0.528
Ppha_1091
KEGG: cch:Cag_1420 glyceraldehyde-3-phosphate dehydrogenase, type I; TIGRFAM: glyceraldehyde-3-phosphate dehydrogenase, type I; PFAM: glyceraldehyde 3-phosphate dehydrogenase; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.
  
 
 0.424
msrA
Peptide methionine sulfoxide reductase; Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.
  
  
 0.423
Ppha_1473
PFAM: low molecular weight phosphotyrosine protein phosphatase; KEGG: cch:Cag_0397 protein tyrosine phosphatase.
  
 
 0.412
Ppha_2863
PFAM: low molecular weight phosphotyrosine protein phosphatase; KEGG: cph:Cpha266_0918 protein tyrosine phosphatase.
  
 
 0.412
Your Current Organism:
Pelodictyon phaeoclathratiforme
NCBI taxonomy Id: 324925
Other names: P. phaeoclathratiforme BU-1, Pelodictyon phaeoclathratiforme BU-1, Pelodictyon phaeoclathratiforme DSM 5477, Pelodictyon phaeoclathratiforme str. BU-1, Pelodictyon phaeoclathratiforme strain BU-1
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