STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Ppha_16855'-Nucleotidase domain protein; PFAM: Alkaline phosphatase; metallophosphoesterase; metalloenzyme domain protein; 5'-Nucleotidase domain protein; SMART: Dystroglycan-type cadherin domain protein; KEGG: cph:Cpha266_1750 5'-nucleotidase domain protein; Belongs to the alkaline phosphatase family. (2852 aa)    
Predicted Functional Partners:
guaB
Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family.
  
 0.761
Ppha_1908
PFAM: OmpA/MotB domain protein; KEGG: pau:PA14_31620 putative ABC-type periplasmic phosphate-binding protein.
 
  
 0.729
Ppha_1680
TIGRFAM: phosphate ABC transporter, inner membrane subunit PstA; PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: cph:Cpha266_1040 phosphate ABC transporter, inner membrane subunit PstA.
 
  
 0.679
secA
Preprotein translocase, SecA subunit; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane; Belongs to the SecA family.
   
 
 0.659
Ppha_2506
KEGG: cbe:Cbei_2837 plasmid pRiA4b ORF-3 family protein.
   
 
 0.659
pstB
Phosphate ABC transporter, ATPase subunit; Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system; Belongs to the ABC transporter superfamily. Phosphate importer (TC 3.A.1.7) family.
  
  
 0.645
Ppha_2072
Purine nucleoside phosphorylase I, inosine and guanosine-specific; The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate.
  
 
 0.639
Ppha_0210
PFAM: glycerophosphoryl diester phosphodiesterase; KEGG: cph:Cpha266_2470 glycerophosphoryl diester phosphodiesterase.
  
  
 0.616
Ppha_1385
KEGG: cph:Cpha266_1319 phosphate-binding protein, putative.
  
  
 0.614
Ppha_1682
TIGRFAM: phosphate binding protein; KEGG: cph:Cpha266_1038 phosphate binding protein.
  
  
 0.614
Your Current Organism:
Pelodictyon phaeoclathratiforme
NCBI taxonomy Id: 324925
Other names: P. phaeoclathratiforme BU-1, Pelodictyon phaeoclathratiforme BU-1, Pelodictyon phaeoclathratiforme DSM 5477, Pelodictyon phaeoclathratiforme str. BU-1, Pelodictyon phaeoclathratiforme strain BU-1
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