Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
Ppha_1696KEGG: cte:CT0885 hypothetical protein. (384 aa)    
Predicted Functional Partners:
Ppha_1422
PFAM: SNF2-related protein; helicase domain protein; SMART: DEAD-like helicases; KEGG: cph:Cpha266_1301 helicase domain protein.
    
 0.834
ndk
Nucleoside-diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family.
    
   0.640
gmk
Guanylate kinase; Essential for recycling GMP and indirectly, cGMP.
    
 0.605
adk
Nucleoside-triphosphate--adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family.
    
 
 0.583
Ppha_1475
TIGRFAM: redox-active disulfide protein 2; KEGG: cch:Cag_0399 redox-active disulfide protein 2.
   
 0.559
Ppha_0642
Hypothetical protein; KEGG: cph:Cpha266_1326 pentapeptide repeat protein.
    
  0.510
Ppha_1056
KEGG: plt:Plut_0829 Legionella vir region protein.
    
  0.510
Ppha_1071
PFAM: Protein phosphatase 2C-like; SMART: protein phosphatase 2C domain protein; KEGG: bth:BT_2772 putative protein phosphatase.
    
  0.510
Ppha_1664
KEGG: cph:Cpha266_1274 hypothetical protein.
  
     0.503
fusA
Translation elongation factor G; Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 s [...]
    
 
 0.501
Your Current Organism:
Pelodictyon phaeoclathratiforme
NCBI taxonomy Id: 324925
Other names: P. phaeoclathratiforme BU-1, Pelodictyon phaeoclathratiforme BU-1, Pelodictyon phaeoclathratiforme DSM 5477, Pelodictyon phaeoclathratiforme str. BU-1, Pelodictyon phaeoclathratiforme strain BU-1
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