Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
Ppha_1792TIGRFAM: addiction module toxin, Txe/YoeB family; PFAM: Addiction module toxin Txe/YoeB; KEGG: gur:Gura_1444 addiction module toxin, Txe/YoeB family. (86 aa)    
Predicted Functional Partners:
Ppha_1791
Hypothetical protein.
       0.773
Ppha_1443
TIGRFAM: addiction module toxin, Txe/YoeB family; addiction module toxin, RelE/StbE family; PFAM: plasmid stabilization system; Addiction module toxin Txe/YoeB; KEGG: fjo:Fjoh_0231 addiction module toxin, Txe/YoeB family.
  
     0.726
Ppha_2586
TIGRFAM: addiction module toxin, Txe/YoeB family; PFAM: plasmid stabilization system; Addiction module toxin Txe/YoeB; KEGG: plt:Plut_1930 addiction module toxin, Txe/YoeB.
  
     0.665
Ppha_1793
KEGG: oan:Oant_1152 hypothetical protein.
       0.601
Ppha_1042
Prevent-host-death family protein; Antitoxin component of a type II toxin-antitoxin (TA) system.
 
 
 0.546
Ppha_0682
Prevent-host-death family protein; Antitoxin component of a type II toxin-antitoxin (TA) system.
  
 
 0.488
Ppha_1595
Prevent-host-death family protein; Antitoxin component of a type II toxin-antitoxin (TA) system.
  
 
 0.488
Ppha_2194
Prevent-host-death family protein; Antitoxin component of a type II toxin-antitoxin (TA) system.
  
 
 0.488
guaB
Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family.
       0.418
Your Current Organism:
Pelodictyon phaeoclathratiforme
NCBI taxonomy Id: 324925
Other names: P. phaeoclathratiforme BU-1, Pelodictyon phaeoclathratiforme BU-1, Pelodictyon phaeoclathratiforme DSM 5477, Pelodictyon phaeoclathratiforme str. BU-1, Pelodictyon phaeoclathratiforme strain BU-1
Server load: low (12%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.