Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
Ppha_1809PFAM: heat shock protein DnaJ domain protein; Gas vesicle synthesis GvpLGvpF; KEGG: plt:Plut_0698 hypothetical protein. (339 aa)    
Predicted Functional Partners:
Ppha_1810
KEGG: plt:Plut_0697 AAA ATPase, CDC48; TIGRFAM: AAA family ATPase, CDC48 subfamily; PFAM: AAA ATPase VAT domain protein; AAA ATPase central domain protein; cell division protein 48 CDC48 domain 2; SMART: AAA ATPase; Belongs to the AAA ATPase family.
 
 
 
 0.938
Ppha_1806
PFAM: Gas vesicle G; KEGG: plt:Plut_0701 hypothetical protein.
 
     0.925
Ppha_1804
PFAM: Gas vesicle synthesis GvpLGvpF; KEGG: plt:Plut_0703 hypothetical protein.
 
     0.885
Ppha_1803
PFAM: gas vesicle protein GVPa; KEGG: plt:Plut_0704 hypothetical protein.
 
     0.882
htpG
Heat shock protein Hsp90; Molecular chaperone. Has ATPase activity.
  
 0.878
Ppha_1801
PFAM: Gas vesicle K; KEGG: plt:Plut_0706 hypothetical protein.
 
     0.869
Ppha_1802
PFAM: Gas vesicle synthesis GvpLGvpF; KEGG: plt:Plut_0705 hypothetical protein.
 
     0.867
Ppha_1232
KEGG: cph:Cpha266_2261 DnaK like protein; Belongs to the heat shock protein 70 family.
  
 0.855
dnaK
Chaperone protein DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family.
  
 0.855
grpE
GrpE protein; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent i [...]
  
 
 0.854
Your Current Organism:
Pelodictyon phaeoclathratiforme
NCBI taxonomy Id: 324925
Other names: P. phaeoclathratiforme BU-1, Pelodictyon phaeoclathratiforme BU-1, Pelodictyon phaeoclathratiforme DSM 5477, Pelodictyon phaeoclathratiforme str. BU-1, Pelodictyon phaeoclathratiforme strain BU-1
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