STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Ppha_1857PFAM: 6-pyruvoyl tetrahydropterin synthase and hypothetical protein; KEGG: cch:Cag_0373 6-pyruvoyltetrahydropterin synthase. (149 aa)    
Predicted Functional Partners:
folE
PFAM: GTP cyclohydrolase I; KEGG: pvi:Cvib_1082 GTP cyclohydrolase I.
  
 
 0.991
queE
Radical SAM domain protein; Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7- deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds.
  
 
 0.970
Ppha_0933
PFAM: short-chain dehydrogenase/reductase SDR; KR domain protein; KEGG: cph:Cpha266_1763 short-chain dehydrogenase/reductase SDR; Belongs to the short-chain dehydrogenases/reductases (SDR) family.
    
  0.903
Ppha_0936
PFAM: 6-pyruvoyl tetrahydropterin synthase and hypothetical protein; KEGG: cph:Cpha266_1847 6-pyruvoyl tetrahydropterin synthase and hypothetical protein.
     
  0.900
Ppha_1700
PFAM: Alkaline phosphatase; KEGG: cph:Cpha266_2693 alkaline phosphatase; Belongs to the alkaline phosphatase family.
     
  0.900
Ppha_1856
Hypothetical protein.
       0.773
queC
exsB protein; Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)). Belongs to the QueC family.
 
  
 0.769
Ppha_0635
Cyclic nucleotide-regulated ABC bacteriocin/lantibiotic exporter; PFAM: cyclic nucleotide-binding; ABC transporter transmembrane region; ABC transporter related; SMART: AAA ATPase; KEGG: cph:Cpha266_1843 cyclic nucleotide-regulated ABC bacteriocin/lantibiotic exporters.
 
  
  0.684
queF
7-cyano-7-deazaguanine reductase; Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1). Belongs to the GTP cyclohydrolase I family. QueF type 1 subfamily.
 
  
 0.675
Ppha_1855
PFAM: OsmC family protein; KEGG: cph:Cpha266_1720 OsmC family protein.
       0.555
Your Current Organism:
Pelodictyon phaeoclathratiforme
NCBI taxonomy Id: 324925
Other names: P. phaeoclathratiforme BU-1, Pelodictyon phaeoclathratiforme BU-1, Pelodictyon phaeoclathratiforme DSM 5477, Pelodictyon phaeoclathratiforme str. BU-1, Pelodictyon phaeoclathratiforme strain BU-1
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