STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Ppha_2048TIGRFAM: hydrogenase expression/formation protein HypE; PFAM: AIR synthase related protein; AIR synthase related protein domain protein; KEGG: cph:Cpha266_0725 hydrogenase expression/formation protein HypE. (347 aa)    
Predicted Functional Partners:
Ppha_2049
TIGRFAM: hydrogenase expression/formation protein HypD; PFAM: hydrogenase formation HypD protein; KEGG: plt:Plut_1455 hydrogenase formation HypD protein.
 
 
 0.997
Ppha_2050
TIGRFAM: hydrogenase assembly chaperone hypC/hupF; PFAM: hydrogenase expression/formation protein (HUPF/HYPC); KEGG: cph:Cpha266_0723 hydrogenase assembly chaperone HypC/HupF.
 
 
 0.995
Ppha_2051
TIGRFAM: [NiFe] hydrogenase maturation protein HypF; PFAM: acylphosphatase; SUA5/yciO/yrdC domain; zinc finger HypF domain protein; KEGG: cch:Cag_0533 hydrogenase maturation protein HypF.
 
 
 0.988
hypA
Hydrogenase nickel insertion protein HypA; Involved in the maturation of [NiFe] hydrogenases. Required for nickel insertion into the metal center of the hydrogenase.
 
  
 0.926
Ppha_2052
TIGRFAM: hydrogenase accessory protein HypB; PFAM: cobalamin synthesis protein P47K; KEGG: cph:Cpha266_0721 hydrogenase accessory protein HypB.
 
  
 0.915
Ppha_2499
PFAM: nickel-dependent hydrogenase large subunit; KEGG: cph:Cpha266_2169 nickel-dependent hydrogenase, large subunit.
 
   
 0.763
Ppha_1861
PFAM: nickel-dependent hydrogenase large subunit; KEGG: plt:Plut_1447 hydrogenase large chain; Belongs to the [NiFe]/[NiFeSe] hydrogenase large subunit family.
 
   
 0.591
Ppha_0695
PFAM: 4Fe-4S ferredoxin iron-sulfur binding domain protein; pyruvate ferredoxin/flavodoxin oxidoreductase; pyruvate flavodoxin/ferredoxin oxidoreductase domain protein; KEGG: cph:Cpha266_0571 pyruvate flavodoxin/ferredoxin oxidoreductase domain protein.
     
 0.524
Ppha_1862
KEGG: cph:Cpha266_0972 hydrogenase (NiFe) small subunit HydA; TIGRFAM: hydrogenase (NiFe) small subunit HydA; PFAM: NADH ubiquinone oxidoreductase 20 kDa subunit; Nickel-iron dehydrogenase small subunit domain protein.
 
   
 0.518
Ppha_1859
TIGRFAM: hydrogenase maturation protease; PFAM: peptidase M52 hydrogen uptake protein; KEGG: plt:Plut_1449 peptidase M52, hydrogen uptake protein.
 
   
 0.498
Your Current Organism:
Pelodictyon phaeoclathratiforme
NCBI taxonomy Id: 324925
Other names: P. phaeoclathratiforme BU-1, Pelodictyon phaeoclathratiforme BU-1, Pelodictyon phaeoclathratiforme DSM 5477, Pelodictyon phaeoclathratiforme str. BU-1, Pelodictyon phaeoclathratiforme strain BU-1
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.